Protein Alignment CG10907 and Ppid

DIOPT Version :10

• Sequence 1: NP_648508.1
• Gene: CG10907 / 39331
• FlyBaseID: FBgn0036207
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_080628.1
• Gene: Ppid / 67738
• MGIID: 1914988
• Length: 370
• Species: Mus musculus
• Alignment Length: 391
• Identity: 106/391 - (27%)
• Similarity: 174/391 - (44%)
• Gaps: 111/391 - (28%)

  Fly    21 VGDIDIELWARECPKACRNFVQLCL--EG---------YYKNTEFHRLVKGFIVQGGD-PNGDGT 73
            ||.|.:||:|...||...||..||.  :|         ::|...|||::|.|::|||| .|.:||
Mouse    29 VGRIVLELFADIVPKTAENFRALCTGEKGTGSTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGT 93

  Fly    74 GGESIYGQPFKDE-FHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKI---- 133
            |||||||:.|:|| ||  .::.|.||:.|||:|.:.||||||.|..|||.|..|:.:||::
Mouse    94 GGESIYGEKFEDENFH--YKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGL 156

  Fly   134 -TGDTIYNM-------LKL-------------------EDGIVD-HQERPMHAHRIVSTEVLSNP 170
             ...|:.|:       .||                   :||..| |.:.|..|      ::....
Mouse   157 GVARTLENVEVNGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDA------DIDLKD 215

  Fly   171 FDDIVPRILSQPSTKSKKTKKERQGVKNFGLLSFGEEAEGDEEETNVYVK--QNAGKAKSLHDVT 233
            .|.|:  ::|             :.:||.|...|  :::..|.....|.|  :....:|::.:..
Mouse   216 VDKIL--LIS-------------EDLKNIGNTFF--KSQNWEMAIKKYAKVLRYVDSSKAVIEKA 263

  Fly   234 DDPKLSKEPIRVP--------KVEKADIEEHLSDDCPEDSVKDKPSTASSDLIKMKLSKRSKSGA 290
            |..:|  :||.:.        |::.::.:..: |.|.|....|..:|.:       |.::::...
Mouse   264 DRSRL--QPIALSCVLNIGACKLKMSNWQGAI-DSCLEALEMDPSNTKA-------LYRKAQGWQ 318

  Fly   291 DKKVQPVEEKSDSEDDEDVLLTREEEQSRKVSEEKSKIREEIASLKKQYQMDKQSKDKLVNGQEK 355
            ..|          |.|:.:   .:.:::::::.....|:.|:..:|   ||.|..|||     ||
Mouse   319 GLK----------EYDQAL---ADLKKAQEIAPGDKAIQAELLKVK---QMIKAQKDK-----EK 362

  Fly   356 A 356
            |
Mouse   363 A 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	71/201 (35%)
		PTZ00121	<279..>426	CDD:173412	16/78 (21%)
		CWC27_CTD	390..451	CDD:412084
Ppid	NP_080628.1	cyclophilin_ABH_like	16..182	CDD:238907	63/154 (41%)
		Chaperone activity. /evidence=ECO:0000250	185..215		6/35 (17%)
		TPR	213..>367	CDD:440225	37/199 (19%)
		Interaction with HSP90AB1. /evidence=ECO:0000250	214..370		37/198 (19%)
		TPR repeat	223..251	CDD:276809	8/42 (19%)
		TPR repeat	272..302	CDD:276809	4/30 (13%)
		TPR repeat	307..335	CDD:276809	5/47 (11%)
		TPR repeat	341..364	CDD:276809	12/31 (39%)