DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10907 and Ppil2

DIOPT Version :9

Sequence 1:	NP_648508.1	Gene:	CG10907 / 39331	FlyBaseID:	FBgn0036207	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_006522510.1	Gene:	Ppil2 / 66053	MGIID:	2447857	Length:	564	Species:	Mus musculus

Alignment Length:	207	Identity:	81/207 - (39%)
Similarity:	115/207 - (55%)	Gaps:	22/207 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVKGFIVQGGDPNGDGTGGES 77
            |.|.|.|..||:::||.....||.|.||::||.:.||..|.|||.::.|::|||||.|.||||||
Mouse   280 GYVRLHTNKGDLNLELHCDLTPKTCENFIKLCKKQYYDGTIFHRSIRNFVIQGGDPTGTGTGGES 344

  Fly    78 IYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKITG--DTIYN 140
            .:|:||||||...|.:|.||::.|||||.:.|.||||.||.....|..|:|:||::.|  ||:..
Mouse   345 FWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAYLDKKHTIFGRVVGGFDTLTA 409

  Fly   141 MLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRI------------------LSQPSTKSK 187
            |..:|..  ...:||.....|.:|.|..:|:::...:|                  :|||...::
Mouse   410 MENVESD--PKTDRPKEEVLICTTTVFVDPYEEADAQIAQERKKTQHQVDPEAKVKMSQPQPGNQ 472

  Fly   188 KTKKERQGVKNF 199
            ..:..||||..:
Mouse   473 GPQTYRQGVGKY 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	73/166 (44%)
Ppil2	XP_006522510.1	RING-Ubox_PPIL2	38..110	CDD:319577
		RING_Ubox	100..159	CDD:388418
		U-box domain, a modified RING finger	103..146	CDD:319361
		cyclophilin_RING	281..440	CDD:238904	72/160 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820