Protein Alignment CG10907 and ppig

DIOPT Version :10

• Sequence 1: NP_648508.1
• Gene: CG10907 / 39331
• FlyBaseID: FBgn0036207
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_998629.1
• Gene: ppig / 406773
• ZFINID: ZDB-GENE-040426-2822
• Length: 687
• Species: Danio rerio
• Alignment Length: 692
• Identity: 165/692 - (23%)
• Similarity: 253/692 - (36%)
• Gaps: 250/692 - (36%)

  Fly    22 GDIDIELWARECPKACRNFVQLCL--EG---------YYKNTEFHRLVKGFIVQGGD-PNGDGTG 74
            |.:.|||::..|||.|.||..||.  :|         :||.|.|||:||.|::|||| ..|:|.|
Zfish    22 GRVVIELFSDVCPKTCENFRCLCTGEKGVGKTTQKPLHYKGTPFHRIVKDFMIQGGDFSEGNGRG 86

  Fly    75 GESIYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGK-ITGDTI 138
            ||||||..|:|...| :::|:..|:.|||.|||.||||||.|..|||.|...:.:||: |||..:
Zfish    87 GESIYGGFFEDGSFS-MKHTKEFLLSMANRGKDTNGSQFFITTKPTPHLDGIHVVFGQVITGQDV 150

  Fly   139 YNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILS----QPSTKSKKTKKERQGV--- 196
            ..|::.:                 .|:..|.|:.::  ::|:    .|.:|:||.||:.|..
Zfish   151 IRMIESQ-----------------KTDTNSRPYAEV--KVLNCGELVPKSKAKKEKKKHQSSSES 196

  Fly   197 --KNFGLLSFGEEAEGDEEETNVYVKQNAGKAKSLHDVTDDPKLSKE-----------PIRVPKV 248
              .:....|..||:|.:::....:.|::..|.:|.|...:.....:|           |..||.:
Zfish   197 EDSSSDSSSDSEESEKEKKRRKKHKKEHKKKKESKHKKKEKKGSDEEEAEPQAVSTIRPEEVPPI 261

  Fly   249 -----------EKADIEEHLSDDCPEDSVKDKP--------------------------STASSD 276
                       ||...||...:....||.:::|                          .|.|..
Zfish   262 PENRFLMRRSPEKPKEEEQSKEKDKVDSGRERPRDRDRERERERERPMANSRPNRTRLVMTRSGR 326

  Fly   277 LIK-------------------------------------------------------------- 279
            .||
Zfish   327 RIKGRGPRRYRTPSRSRSRSWDRFRRSETPPHWRHEMQRTQKAKANLAASQERWIKGDKGDMSEE 391

  Fly   280 ----------------------------MKLSKRSKS-----GADKKVQPVEEKSDSED-----D 306
                                        .|:|||.||     |.|:|......||...|     |
Zfish   392 KTKTTELSSVNKARGDKQDTARKNSEQEKKVSKRDKSRSPSKGRDRKRDKHRSKSRERDARKKPD 456

  Fly   307 EDVLLTREEEQSRKVSEEKSKIREEIASLK--------------------KQYQMDKQSKDKLVN 351
            .|.    |:::||..|:.|.|.||:..|.|                    |:.:...:||::..:
Zfish   457 ADA----EKKKSRSRSKSKDKKREKEKSKKPDDKRGRSASKEKDRKEKNDKEVEQKDRSKERAKD 517

  Fly   352 GQEKAAKSNEIKGSSENHYINDFIESKEK---YTAKVKLQPKGQ---------------SREAFT 398
            |:::.:|..|.|.:.|    .:...||||   .:.:.:.:.:||               |||..|
Zfish   518 GEKEKSKEVEKKKNGE----RERSRSKEKGRDVSRRSRSRGRGQRGQSRDRGRDRRHSSSRERKT 578

  Fly   399 LSLLSKFRTKLDNLKQKSSSDDGESEPKDIDDRVVEQEIIGDDWLSHTLNFNSTTPVLAKDANKK 463
             |..|:.|       :::...|.|...|..|::  .:|..|.|..|...:.........:|..|:
Zfish   579 -SHRSRSR-------ERARGRDAEDRRKSADNK--SRETRGRDRSSKERSSQKQRSREREDRQKR 633

  Fly   464 GDDWYDAYDPRNPLNKRKRGETGSSKSS----SGKSKSSKRD 501
            ..|..|.....:..:|||:.:|..|..|    ..||||.::|
Zfish   634 RKDKSDTGSSDSDNDKRKKRKTSDSPKSKERAKDKSKSPRKD 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	66/168 (39%)
		PTZ00121	<279..>426	CDD:173412	48/284 (17%)
		CWC27_CTD	390..451	CDD:412084	17/75 (23%)
ppig	NP_998629.1	cyclophilin	8..175	CDD:469651	67/172 (39%)
		PRK12678	430..>644	CDD:237171	51/231 (22%)