DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10907 and ppil2

DIOPT Version :9

Sequence 1:	NP_648508.1	Gene:	CG10907 / 39331	FlyBaseID:	FBgn0036207	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_957285.2	Gene:	ppil2 / 393966	ZFINID:	ZDB-GENE-040426-1096	Length:	524	Species:	Danio rerio

Alignment Length:	251	Identity:	89/251 - (35%)
Similarity:	145/251 - (57%)	Gaps:	20/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YIQEPPTSGKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVKGFIVQGGDPN 69
            |:::   .|.|.|.|..||:::||...:.|||..||::||.:|||..|.|||.::.|::|||||.
Zfish   275 YVKK---KGYVRLHTNKGDLNVELHCDKVPKAGENFIKLCKKGYYDGTVFHRSIRNFMIQGGDPT 336

  Fly    70 GDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKIT 134
            |.||||||.:|:||||||...|.:|.||::.|||||.:.|.||||.||.....|..|:::||::.
Zfish   337 GTGTGGESFWGKPFKDEFRPNLSHTGRGILSMANSGPNTNKSQFFITFRSCAYLDRKHSVFGRVV 401

  Fly   135 G--DTIYNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILSQPSTKSKKTKKERQGVK 197
            |  :|:..|..:|..  ...::|....:|:||.|..:|:::...:|.::...:::|.::||  .:
Zfish   402 GGLETLSAMENVESD--PKTDKPKSEIKILSTSVFVDPYEEADAQIAAEREKEAQKVEEER--AQ 462

  Fly   198 NFGLLSFGEEAEGDEEE------TNVYVKQNAGKAKSLHDVTDDPKLSKEPIRVPK 247
            ...|::   :|:.:|:.      ...|:..:|  .|..|...:.|..|:.|.:.||
Zfish   463 TSALVN---KAKTEEKPKAFRPGVGKYINMSA--TKHSHPDAEKPSTSEAPAKKPK 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	72/171 (42%)
ppil2	NP_957285.2	Ubox	42..96	CDD:128780
ppil2	NP_957285.2	cyclophilin_RING	281..440	CDD:238904	71/160 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820