DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10907 and Cyp40

DIOPT Version :10

Sequence 1:NP_648508.1 Gene:CG10907 / 39331 FlyBaseID:FBgn0036207 Length:502 Species:Drosophila melanogaster
Sequence 2:NP_648338.1 Gene:Cyp40 / 39121 FlyBaseID:FBgn0036020 Length:383 Species:Drosophila melanogaster


Alignment Length:421 Identity:100/421 - (23%)
Similarity:155/421 - (36%) Gaps:133/421 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 TSGKVLLKTTVGDID-----IELWARECPKACRNFVQLCLEG----------YYKNTEFHRLVKG 60
            |:..|.|..::|..|     |||.....||...||..||...          :||.|:||::.:.
  Fly    13 TNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRV 77

  Fly    61 FIVQGGD-PNGDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMANSGK-DDNGSQFFFTFAPTPEL 123
            |:||.|| ...||:.||||||..|.|| :..|.:...|:|.|||.|| :.|.||||.:.|....|
  Fly    78 FVVQSGDVVKNDGSSGESIYGPVFDDE-NFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENL 141

  Fly   124 QNKNTLFGKI----------------TGDTIYNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFD 172
            ...|.:.|::                .||....::..:.|.:.|.|         ...:..|  |
  Fly   142 NGTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEIAHNE---------DWGIECN--D 195

  Fly   173 DIVPRILSQPSTKSKKTKK------------ERQGVKNFGLLSFGEEAEGDEEETNVYVKQNAGK 225
            :...::.:.|....:|..|            .||...:|..|....||.....:.|.|...    
  Fly   196 ETTDKLPAYPQDWPRKLDKFTGDGAVELLTGIRQSGNHFYQLGRYHEARAKYRKANRYYHY---- 256

  Fly   226 AKSLHDVTDDPKLSKE-------PIRVPKVEKADIEEHLSDDCPED-------SVKDKPSTASSD 276
                        ||::       |::          :||.|   ||       ||.:..:.|:.|
  Fly   257 ------------LSRQFGWQQLNPLK----------KHLVD---EDLLKVDGFSVVNNINAAAVD 296

  Fly   277 L-----------------IKMKLSKR--SKSGADKKVQPVEEK-SDSEDDEDVLLTREEEQSRKV 321
            |                 :..|.||.  .::.|.:.::..||. :|.:...::|           
  Fly   297 LKVGNYTSAREVCNEAIRLDPKCSKAFYRRAQAQRGLRNYEEAINDLKTAHNLL----------- 350

  Fly   322 SEEKSKIREEIASLKKQY-QMDKQSKDKLVN 351
             .|..:|..|:.|.|:.. |.::|.::.|.|
  Fly   351 -PENKQILNELNSTKQLLAQYNRQQRNALKN 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10907NP_648508.1 cyclophilin_CeCYP16-like 8..178 CDD:238906 59/199 (30%)
PTZ00121 <279..>426 CDD:173412 17/77 (22%)
CWC27_CTD 390..451 CDD:412084
Cyp40NP_648338.1 cyclophilin 15..181 CDD:469651 53/166 (32%)
TPR 231..>370 CDD:440225 32/179 (18%)
TPR repeat 285..315 CDD:276809 5/29 (17%)
TPR repeat 320..346 CDD:276809 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.

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