DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10907 and CG7747

DIOPT Version :9

Sequence 1:	NP_648508.1	Gene:	CG10907 / 39331	FlyBaseID:	FBgn0036207	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	101/277 - (36%)
Similarity:	149/277 - (53%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVKGFIVQGGDPNGDGTGGES 77
            |.|.|.|.:|.:::||:..:.|:||.||::.|..|||.|..|||.::.||||||||.|.|:||||
  Fly   280 GYVRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSIRNFIVQGGDPTGSGSGGES 344

  Fly    78 IYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPTPELQNKNTLFGKITG--DTIYN 140
            |:|:.|:|||...|.:|.||::.|||||.:.||||||.|:.....|..|:|:|||:.|  ||:..
  Fly   345 IWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLVGGLDTLQK 409

  Fly   141 MLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILSQPSTKSKKTKKERQGVKNFGLLSFG 205
            |..:|   ||:::||:....|.|::|..|||           :..:::..|||:
  Fly   410 MENIE---VDNKDRPIEDIIIESSQVFVNPF-----------AEAAEQLAKERE----------- 449

  Fly   206 EEAEGDEEETNVYVKQNAGKAKSLHDVTDDPKLSKEPIRVPKVEKADIEEHLSDDCPEDSVKDKP 270
            |||.|.||    .||:.           :..|..|||:   ||.:..:.::|.    ..:|..||
  Fly   450 EEAAGKEE----IVKKE-----------EQQKRMKEPL---KVYREGVGKYLK----LQTVAKKP 492

  Fly   271 STASSDLIKMKLSKRSK 287
               .:.|...:.:|:.|
  Fly   493 ---EAPLTSAQAAKKKK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	77/166 (46%)
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	76/171 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447190
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45625
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850