Protein Alignment twy and fbf1

DIOPT Version :10

• Sequence 1: NP_648507.1
• Gene: twy / 39330
• FlyBaseID: FBgn0036206
• Length: 928
• Species: Drosophila melanogaster
• Sequence 2: XP_004918509.1
• Gene: fbf1 / 100127655
• XenbaseID: XB-GENE-958098
• Length: 1113
• Species: Xenopus tropicalis
• Alignment Length: 1032
• Identity: 223/1032 - (21%)
• Similarity: 420/1032 - (40%)
• Gaps: 234/1032 - (22%)

  Fly     5 DDPLAELLSDNSLDNDNFFETPAGVGHKKPAKLAKPKGKLEDLFGIQEETEADVQGQGTGARKTP 69
            :||||.:||    |.|:..:           |..||:|          .|..:.......:..|.
 Frog   176 NDPLAGILS----DEDDLVD-----------KKIKPRG----------STATEKPKSAPESAPTK 215

  Fly    70 NAISTPRIVKQKPSISL-----------DDDLVEDDDLGFD--PKRPKSGGTKRSLFDDLLTSNA 121
            :|.:.| |...|||::.           .|||:  |.||||  |:|.:   .|.|       |..
 Frog   216 SADNLP-ISPAKPSLTTLKKDEFNFGEETDDLM--DALGFDNSPERTR---VKES-------SAP 267

  Fly   122 EPKKNIFDEILA-GDAVK---RPATSK-------PSMSRQ---------------STDTTTDNSQ 160
            .|.::..||:|. |.|.|   ||.|.:       |...:|               |...|.::.:
 Frog   268 PPARSKLDELLGRGTAAKLLERPPTGERKEFKLDPKYQKQQENQNTPDDADINFGSYQPTVNSPE 332

  Fly   161 ARPKTSTGRRSSAQSATINMNADPLGLFGRDTNATVSGMSTPVSKKRGTTADWLGLEQE----PD 221
            .||......|.||..:. |..::     ||..::|.:..| |...:|| .||||||:.:    ||
 Frog   333 GRPSRRPSVRFSADGSD-NFKSE-----GRSRSSTPATRS-PARGERG-GADWLGLKDDDIDVPD 389

  Fly   222 QRPITP---KAQTAKAQPSSESPSKNTADILRLPDSDENGMEQEAEMAAVPAPSVVTAATQNILM 283
            ..|..|   ..::|...|||.....:...|...|.:......|||...|......:|
 Frog   390 FTPSLPVRDPPRSAGVTPSSAGRPTSGNKIADKPINQTRSGLQEAASVAQEDDGWLT-------- 446

  Fly   284 LSNLNLESNHKFNALQQQEAQLVIAAQMKSQERTLLEMQRRQEDQDRKFQALIQQQLQRQQQMEE 348
                        :||.|::||     :.:.:|::  :.|.||||......|:..|...::..:.:
 Frog   447 ------------SALSQKKAQ-----KQEMEEKS--KSQARQEDVTGSSPAVFSQTSSQESAVNK 492

  Fly   349 ----------HIKGQQERINMHLQLMMSQPVRV----------------QDVVSTPPLVEKPEPE 387
                      .:.|..::::..:.....:.::.                |.|||.|  :|:...:
 Frog   493 GTRETGMVVAEVSGSPKKVSTFVAPKQEETIQTAVTGPSQEHGTARTLQQTVVSRP--LERKARD 555

  Fly   388 PERKEHHKATSQEQEHLLLLEMDAKRNLLEKQRLDELVANMKVNYEQEIEMIDSSYKKQIKVLEE 452
            .:| :.|....|.|..::.||...::..||:.:.:.|:..::..:::::|:|:::::.::|::|:
 Frog   556 GDR-DLHGDPLQAQNRVMDLEAQVRKLQLERDQQNLLLETLRERHQEDMELIENAHRSRLKLVED 619

  Fly   453 HLSVVEKRLKDENSELRQYYIEKLEKQKED-------YVEQISSLRQDHEDEVRKLRQ------- 503
            .....|:||:.||.||...|:.:.:..:.:       |.::::..:|:.|.|:.::|:
 Frog   620 SARQREERLRLENQELSAQYLSRCQSTETEKAELLAQYQKKLTEFQQEKELELERIRELQRVFVQ 684

  Fly   504 ----SHELDLEGIRQAKMVELSAVQDHGNYLDTLRLASSNLQELRDGMSD--------NQERERQ 556
                .||..|:.:::.|..|:.||....::..:|......::.....:||        .|....:
 Frog   685 EMCRDHEEQLQRLKRLKDQEIDAVTSASSHTRSLNTVIEQMESFSHKLSDLSHRVESTQQTTSHE 749

  Fly   557 LEA----RERRLADQERRLKMDEETADDEKRRLMELVSTLELQLGRLSKESAEENWQLRQRMSSL 617
            ||.    ||.:|...:.:|...::..:.|:..|..:::.:|.:|...|:...:|.|::....:.:
 Frog   750 LETGARQREGQLRALQEQLSRQQKDMEQERNSLRMVITNMETRLIEQSRLLEQERWRVTSEQAKV 814

  Fly   618 EAERKAFEREKEFHREQMQRDEKRVEDLKALQLAEMERLHHDLQEERNQLTVERQQIELRQQLNE 682
            |:.:::.|.::....:||..:.:.:|..|:..|.|.:.:.....|||.:|..|......:|:|:
 Frog   815 ESLQRSLEEQRRVVTQQMAIEREELERAKSALLEEQQSVMSRCTEERRKLAAEWSDFHTQQKLS- 878

  Fly   683 HGDPDRDRRELEAQLQVAREAIRRADEERD----RYHKLQREMEQRKRHLLDKEHALNLKEDELG 743
                 ::|.|.||...:.      |:.:|:    ...|.|.|::.:...||:||..|.|..:.:.
 Frog   879 -----KERAEKEANRVIV------AETQREGAIINLAKEQAELKIKASELLNKEEQLFLAREAME 932

  Fly   744 QATGAYRLATSR------------------QHLAEQKAREADQLL----------QAKLKVMAKR 780
            :.....||...|                  ..||.|:..|.::.|          |.:|:.:.::
 Frog   933 KERQDLRLEKERVNASALRVRQRAEEIESMSKLASQRYEEGEKALEEACKIESEHQGRLRAIQQK 997

  Fly   781 AQEIAEKEAQLAHERMLVAQDRMALVNLKKQISRSRCAICKMGAESAEIAQR-----RANVNPTA 840
            .:.:.::|..:..||:.:||.|..|..|::::..:.........|...:||.     :|...|.|
 Frog   998 LEILRQQEEHIHQERLSLAQQRRQLNQLQQELPTASVLFPARPPEPPLMAQNGKFTAKAIGIPAA 1062

  Fly   841 ATDLQLPQVTPSHAEL-LLKMSQEPGQVQSDIVDRMLDENIEASYRRMYNAPPSSSI 896
            ..:...||||..||:| |||||.:..:      |.:.:|.......|..|.|.|.::
 Frog  1063 LQETSKPQVTEFHAKLALLKMSAQQDR------DFLEEEQAFLETLRKPNLPWSQAV 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twy	NP_648507.1	PRK12323	<139..320	CDD:481241	47/209 (22%)
		COG2433	<416..>502	CDD:441980	19/92 (21%)
		Smc	<467..>805	CDD:440809	78/399 (20%)
fbf1	XP_004918509.1	Smc	<566..>1047	CDD:440809	97/492 (20%)