DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc68D and Gm30500

DIOPT Version :9

Sequence 1:	NP_648504.2	Gene:	Muc68D / 39326	FlyBaseID:	FBgn0036203	Length:	1514	Species:	Drosophila melanogaster
Sequence 2:	XP_017171830.1	Gene:	Gm30500 / 102632425	MGIID:	5589659	Length:	614	Species:	Mus musculus

Alignment Length:	416	Identity:	96/416 - (23%)
Similarity:	142/416 - (34%)	Gaps:	128/416 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1113 PCTTD--NPSSLEPS-----PSTPGNDDDSGNSGSENGNSSTSGSPCTTD----------NPSDP 1160
            ||...  ||..|..|     |..||:     ..|.|| .:..|| ||...          .|.|.
Mouse   244 PCPRGYYNPDPLTHSLDSCLPCPPGH-----YCGQEN-LTKPSG-PCDAGWYCVSAAWNARPFDL 301

  Fly  1161 ESSSST----PGNDDDSGNSGSENGNSSTSGSPCTTDNPSDPESSSSTPGNDDDSGNSGSESGIT 1221
            ::.:||    |         .:..|....:||.|.   ...||....||      |:..:.||:.
Mouse   302 DNYTSTNCLCP---------ATATGGKCPAGSYCP---EGSPEPIPCTP------GSFCATSGLP 348

  Fly  1222 STTG---APY----TTDNPASQEPSPSAPENPGDSGNSSSESPPEGATPCT----PNAPKKSTTS 1275
            :.||   |.|    .:::||..:.....|..||.....:|..|    |||.    .:.|:::|:|
Mouse   349 TPTGPCQAGYFCIGGSESPAPVDEVTGGPCPPGSYCPVASHKP----TPCPVGTFSSLPEQTTSS 409

  Fly  1276 SYTAHPTPKYTTEGNKAETSTLKSPTGTTP-GHQEDRTDCSNMPNGIFLRDFQ--SCNKYYVCLN 1337
            :..:.|:..|..|..      |::|:|..| |:.   .|.|..|    ::||.  .|.:.|.|..
Mouse   410 TCRSCPSGFYCKEAG------LQAPSGWCPAGYY---CDSSTGP----VQDFSLYPCPRGYYCPV 461

  Fly  1338 G--KAIAGHCPRNLHFDIKRKVCNFPSLVDCPLDEAPE--------------------NVTKK-- 1378
            |  ||:...||...:...|    ...|:.:|.|..|.:                    |:..|
Mouse   462 GTTKAMYHSCPVGTYGPRK----GLTSITECQLCPAGKFCSLAGISAPTGKVQTALGLNMVSKGL 522

  Fly  1379 ---PSDTESTPDCKSLRNGAYVRDPKSCSRFYVCANG--------RAIPRQCPQGLHFDIKSNFC 1432
               |..|.|..:......||....|.|..:..:.|:.        :|:..|....|...::..
Mouse   523 EAYPDRTSSLQESVLQGTGAKQDLPASTPQMGLGASAAPQDTTVLKALQSQPRAHLELGLQKE-- 585

  Fly  1433 NYPILVQCSLEESQADAHGALLAEGV 1458
                      .|:|.||..|||...|
Mouse   586 ----------PEAQRDAGSALLDNSV 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc68D	NP_648504.2	ChtBD2	21..69	CDD:214696
		PHA03249	1088..>1209	CDD:223023	29/116 (25%)
		CBM_14	1314..1366	CDD:279884	14/55 (25%)
		CBM_14	1388..1440	CDD:279884	8/59 (14%)
		ChtBD2	1459..1505	CDD:214696	96/416 (23%)
Gm30500	XP_017171830.1	TNFRSF	394..518	CDD:389949	31/140 (22%)
		CRD1	394..411	CDD:276900	4/16 (25%)
		CRD2	414..451	CDD:276900	13/49 (27%)
		CRD3	453..506	CDD:276900	13/56 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010