DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bmcp and Slc25a30

DIOPT Version :9

Sequence 1:	NP_648501.1	Gene:	Bmcp / 39322	FlyBaseID:	FBgn0036199	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	XP_006519518.1	Gene:	Slc25a30 / 67554	MGIID:	1914804	Length:	311	Species:	Mus musculus

Alignment Length:	269	Identity:	149/269 - (55%)
Similarity:	183/269 - (68%)	Gaps:	17/269 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DWRPFVYGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALY 70
            :|:||||||:||||||.||||||.||||||||||..|.:|.::|||||..|.::|.|||||:|||
Mouse     5 NWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDANFREIRYRGMLHALMRIGREEGLKALY 69

  Fly    71 SGIWPAVLRQATYGTIKFGTYYTLKKLANERGLLINEDGSERVWSNILCAAAAGAISSAIANPTD 135
            |||.||:||||:|||||.|||.:||:||.||    .||  |.:..|::|...:|.||||||||||
Mouse    70 SGIAPAMLRQASYGTIKIGTYQSLKRLAVER----PED--ETLLVNVVCGILSGVISSAIANPTD 128

  Fly   136 VLKVRMQVHGKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCK--LQLM 198
            |||:|||........|::..|..||:.||.||||:||..|||||.::..|||||||..|  |.|.
Mouse   129 VLKIRMQAQNSAVQGGMIDSFMSIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILS 193

  Fly   199 NAFGDHVGNHFISSFIASLGSAIASTPIDVIRTRLMNQRPVSITMNGVVTAAATPKLYSGSLDCA 263
            ...||.|..||:|||...|..|:||.|:||:|||:||||.:   .:|....      |.|:|||.
Mouse   194 GLMGDTVATHFLSSFTCGLVGALASNPVDVVRTRMMNQRAL---RDGRCAG------YKGTLDCL 249

  Fly   264 VQTIRNEGL 272
            :|...:.||
Mouse   250 LQVSVSAGL 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bmcp	NP_648501.1	Mito_carr	7..97	CDD:278578	65/89 (73%)
		Mito_carr	<132..199	CDD:278578	37/68 (54%)
		Mito_carr	204..303	CDD:278578	29/69 (42%)
Slc25a30	XP_006519518.1	Mito_carr	6..96	CDD:365909	65/89 (73%)
		Mito_carr	105..191	CDD:365909	44/85 (52%)
		Mito_carr	199..>259	CDD:365909	29/69 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4737
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57046
Inparanoid	1	1.050	335	1.000	Inparanoid score	I2388
Isobase	1	0.950	-	0	Normalized mean entropy	S1382
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D1126848at2759
OrthoFinder	1	1.000	-	-		FOG0005838
OrthoInspector	1	1.000	-	-		otm44165
orthoMCL	1	0.900	-	-		OOG6_103926
Panther	1	1.100	-	-	LDO	PTHR45618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	1	1.000	-	-		X4231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820