DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bmcp and slc25a10b

DIOPT Version :9

Sequence 1:	NP_648501.1	Gene:	Bmcp / 39322	FlyBaseID:	FBgn0036199	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_957466.1	Gene:	slc25a10b / 394147	ZFINID:	ZDB-GENE-040426-1095	Length:	286	Species:	Danio rerio

Alignment Length:	300	Identity:	88/300 - (29%)
Similarity:	139/300 - (46%)	Gaps:	39/300 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALYSGIWPA 76
            :||:||..|...|.|:|..|..||.| |::     ::|..||.   :.:.:.:|..|||||:..:
Zfish    11 FGGIASCGAACCTHPLDLIKVHLQTQ-QEV-----KMRMMGMA---IHVVKNDGFLALYSGLSAS 66

  Fly    77 VLRQATYGTIKFGTYYTLKKLANERGLLINEDGSERVWSNILCAAAAGAISSAIANPTDVLKVRM 141
            :.||.:|...:|..|.|::.....     ...|....:..:|..|..|.....|..|.|::.|||
Zfish    67 LCRQMSYSLTRFAIYETVRDTLGS-----GSQGPMPFYQKVLLGAFGGFTGGFIGTPADMVNVRM 126

  Fly   142 Q------VHGKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCKLQLMNA 200
            |      :..:..:|..|.....:::.||.|.|:.|....:.|..::...:|..||..|..::..
Zfish   127 QNDVKLPLEQRRNYKHALDGLFRVWREEGTRRLFSGATMASSRGALVTVGQLACYDQAKQLVLGT 191

  Fly   201 --FGDHVGNHFISSFIASLGSAIASTPIDVIRTRLMNQRPVSITMNGVVTAAATPKLYSGSLDCA 263
              .||::..||:|||||...:.....|:||::|||||.:..                |.|.:.|.
Zfish   192 GLMGDNILTHFLSSFIAGGCATFLCQPLDVLKTRLMNSKGE----------------YRGVMHCL 240

  Fly   264 VQTIRNEGLPALYKGFIPTWVRMGPWNIIFFITYEQLKKY 303
            .:|.: .|..|.|||.:|..:|:.|..|:.|:..||||||
Zfish   241 SETAK-LGPLAFYKGLVPAGIRLIPHTILTFVFLEQLKKY 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bmcp	NP_648501.1	Mito_carr	7..97	CDD:278578	28/84 (33%)
		Mito_carr	<132..199	CDD:278578	18/72 (25%)
		Mito_carr	204..303	CDD:278578	33/98 (34%)
slc25a10b	NP_957466.1	PTZ00169	12..278	CDD:240302	85/296 (29%)
		Mito_carr	12..92	CDD:278578	28/93 (30%)
		Mito_carr	<118..190	CDD:278578	18/71 (25%)
		Mito_carr	197..281	CDD:278578	34/99 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.930