DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bmcp and slc25a14

DIOPT Version :9

Sequence 1:	NP_648501.1	Gene:	Bmcp / 39322	FlyBaseID:	FBgn0036199	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	XP_017208245.1	Gene:	slc25a14 / 393133	ZFINID:	ZDB-GENE-040426-749	Length:	335	Species:	Danio rerio

Alignment Length:	299	Identity:	169/299 - (56%)
Similarity:	206/299 - (68%)	Gaps:	22/299 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DWRPFVYGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALY 70
            :|:||||||:|||.|||||||||.||||||:|||   ....::|||||..|.::|.||||:||||
Zfish    54 NWKPFVYGGMASIVAEFGTFPIDLTKTRLQVQGQ---THCMEVRYRGMFHALLRIGREEGVRALY 115

  Fly    71 SGIWPAVLRQATYGTIKFGTYYTLKKLANERGLLINEDGSERVWSNILCAAAAGAISSAIANPTD 135
            |||.||:||||:|||||.|||.||||      |.::....|.:..|:.|...:|.:||::|||||
Zfish   116 SGISPALLRQASYGTIKIGTYNTLKK------LFVSHPEEETMVINVFCGVVSGVLSSSLANPTD 174

  Fly   136 VLKVRMQVHGKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCKLQLMNA 200
            |||:|||..|......::..|..||:.||.|||||||.||||||.::..|||||||..|..|:.:
Zfish   175 VLKIRMQAQGSLLQGSMMSNFMNIYQTEGTRGLWRGVIPTAQRAAIVVGVELPVYDITKKHLIRS 239

  Fly   201 --FGDHVGNHFISSFIASLGSAIASTPIDVIRTRLMNQRPVSITMNGVVTAAATPKLYSGSLDCA 263
              .||.|..||||||...|..|:||.|:||:|||:||||          ..|..| ||.|:||..
Zfish   240 GLMGDTVLTHFISSFTCGLAGALASNPVDVVRTRMMNQR----------VLAGNP-LYKGTLDGL 293

  Fly   264 VQTIRNEGLPALYKGFIPTWVRMGPWNIIFFITYEQLKK 302
            :||.||||..||||||.|.|:|:||||||||:|:|||||
Zfish   294 MQTWRNEGFFALYKGFWPNWLRLGPWNIIFFMTFEQLKK 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bmcp	NP_648501.1	Mito_carr	7..97	CDD:278578	63/89 (71%)
		Mito_carr	<132..199	CDD:278578	38/66 (58%)
		Mito_carr	204..303	CDD:278578	57/99 (58%)
slc25a14	XP_017208245.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5149
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2643
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D477054at33208
OrthoFinder	1	1.000	-	-		FOG0005838
OrthoInspector	1	1.000	-	-		oto40393
orthoMCL	1	0.900	-	-		OOG6_103926
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	1	1.000	-	-		X4231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870