DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11658 and fbxo32

DIOPT Version :9

Sequence 1:	NP_648498.1	Gene:	CG11658 / 39319	FlyBaseID:	FBgn0036196	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_957211.1	Gene:	fbxo32 / 393891	ZFINID:	ZDB-GENE-040426-1040	Length:	356	Species:	Danio rerio

Alignment Length:	392	Identity:	104/392 - (26%)
Similarity:	177/392 - (45%)	Gaps:	81/392 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAFISKDFRSPGETWIKTDGGWER---------SKVLECGGKRKRHHSEGSSSYQDSDSSEEEAV 56
            |.|:.:|:||||::|:||:.||::         :.|||    ||        ||...:..:|..:
Zfish     1 MPFLGQDWRSPGQSWVKTEDGWKKTTKDDNETNNNVLE----RK--------SYCKEEHDKENLI 53

  Fly    57 MPPHYHITIR---------------------------CTREIAGFNGLSEAVKRLDFRRSVRDRK 94
            :..:|.:..:                           .|:|..|:..|.||..||||..:::|.:
Zfish    54 LSINYDVAAKKRKKDLPNNNTKIPYFYKDKWIYVHKGSTKERHGYCTLGEAFNRLDFCSAIKDTR 118

  Fly    95 RFHYICAFLLLVSNKGIASLPGSAQRQLLQMVEEVASHVNDSQQH----PNVLRGLALKLEHIVS 155
            ||:|:...|.|::...:.||.|.||:..:.::|.|...|.|.||:    ..:|:.|...|..:|.
Zfish   119 RFNYVVRLLELIAKSQLPSLSGVAQKNYMNILERVVQKVLDDQQNVRPIKELLQTLYASLCSLVQ 183

  Fly   156 QENQKCWGKP--LGSTYLWKEHMATIKRIQRVASQIEIREPDPEAKPKLHELPEECVREIILCIA 218
            .     .||.  :|:..:|...|..|.:.|:....|:|..|.......| |||......|:..::
Zfish   184 D-----MGKSVLVGNINIWVHRMENILQWQQQLDNIQINRPKNTGMTLL-ELPVSLQLNIMQRLS 242

  Fly   219 DHRDLESAAEAWETMAKLVSEQRIWRELTRFHFNQRQIH-TILDLDKFKQMGEIKDWKQIYHQLR 282
            |.|||.|..:....::.|..::.:|::|.::||..|||. .::..||    |:: :||::|.:|.
Zfish   243 DGRDLVSLGQVCPDLSMLTEDRLLWKKLCQYHFTDRQIRKRLMVSDK----GQL-EWKKMYFKLC 302

  Fly   283 RTYGVNDDYQFAEVLALCRSCCCLFWPSDGHPCIVDQSPDYKQRLEEAGGQLALAQPVPPAQFLK 347
            |.|...:  |:::.|..|..|..|||....|||..: :|:            :..:.|.|..|:.
Zfish   303 RCYPHKE--QYSDTLQFCTHCHILFWKDTDHPCTAN-NPE------------SCCKAVSPQGFIN 352

  Fly   348 YF 349
            .|
Zfish   353 LF 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11658	NP_648498.1	None
fbxo32	NP_957211.1	F-box-like	226..272	CDD:289689	13/46 (28%)
fbxo32	NP_957211.1	Elongin_A	<254..>303	CDD:284333	15/53 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595415
Domainoid	1	1.000	128	1.000	Domainoid score	I5273
eggNOG	1	0.900	-	-		E1_KOG3926
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4468
OMA	1	1.010	-	-		QHG46083
OrthoDB	1	1.010	-	-		D280011at33208
OrthoFinder	1	1.000	-	-		FOG0002870
OrthoInspector	1	1.000	-	-		otm24741
orthoMCL	1	0.900	-	-		OOG6_108752
Panther	1	1.100	-	-	LDO	PTHR13123
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3549
SonicParanoid	1	1.000	-	-		X2229
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800