Protein Alignment CG11658 and FBXO25

DIOPT Version :9

• Sequence 1: NP_648498.1
• Gene: CG11658 / 39319
• FlyBaseID: FBgn0036196
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_904357.1
• Gene: FBXO25 / 26260
• HGNCID: 13596
• Length: 367
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 95/399 - (23%)
• Similarity: 170/399 - (42%)
• Gaps: 84/399 - (21%)

  Fly     1 MAFISKDFRSPGETWIKTDGGWERSKVLECGGKRKRHHSEGSSSYQDSDSSEEEAVMPPHYH--- 62
            |.|:.:|:||||.:||||:.||:|.:  .|..|.:|.::..:.|:....:||:..:.....|
Human     1 MPFLGQDWRSPGWSWIKTEDGWKRCE--SCSQKLERENNRCNISHSIILNSEDGEIFNNEEHEYA 63

  Fly    63 -------------------------ITIRCTREIAGFNGLSEAVKRLDFRRSVRDRKRFHYICAF 102
                                     :....|:|..|:..|.||..||||..:::|.:||:|:...
Human    64 SKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKL 128

  Fly   103 LLLVSNKGIASLPGSAQRQLLQMVEEVASHVNDSQQHPNVLRGLALKLEHI-----------VSQ 156
            |.|::...:.||.|.||:....:::::...|.|...:|.:::.|...|...           |..
Human   129 LQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLV 193

  Fly   157 ENQKCWGKPLGSTYLWKEHMATIKRIQRVASQIEIREPDPEAKPKLHELPEECVREIILCIADHR 221
            .|...|...|.:...|::.:..::..::|.:.:           .|.:||...:..|:...:|..
Human   194 GNINIWICRLETILAWQQQLQDLQMTKQVNNGL-----------TLSDLPLHMLNNILYRFSDGW 247

  Fly   222 DLESAAEAWETMAKLVSEQRIWRELTRFHFNQRQI--HTILDLDKFKQMGEIKDWKQIYHQLRRT 284
            |:.:..:...|:..|..::::|::|.::||.::|.  |.||     .:.|.| :||.:|..|::.
Human   248 DIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLIL-----SEKGHI-EWKLMYFALQKH 306

  Fly   285 YGVNDDYQFAEVLALCRSCCCLFW---------PSDGHPCIVDQSPDYKQRLEEAGGQLALAQPV 340
            |...:  |:.:.|..||.|..|||         ...||||.. ..||            :...||
Human   307 YPAKE--QYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTA-ADPD------------SCFTPV 356

  Fly   341 PPAQFLKYF 349
            .|..|:..|
Human   357 SPQHFIDLF 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11658	NP_648498.1	None
FBXO25	NP_904357.1	Interaction with beta-actin	1..83		21/83 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159290
Domainoid	1	1.000	133	1.000	Domainoid score	I5080
eggNOG	1	0.900	-	-		E1_KOG3926
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41649
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4607
Isobase	1	0.950	-	0	Normalized mean entropy	S5943
OMA	1	1.010	-	-		QHG46083
OrthoDB	1	1.010	-	-		D280011at33208
OrthoFinder	1	1.000	-	-		FOG0002870
OrthoInspector	1	1.000	-	-		otm40908
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13123
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3549
SonicParanoid	1	1.000	-	-		X2229
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.890