DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11658 and Fbxo32

DIOPT Version :9

Sequence 1:	NP_648498.1	Gene:	CG11658 / 39319	FlyBaseID:	FBgn0036196	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_598205.1	Gene:	Fbxo32 / 171043	RGDID:	620373	Length:	350	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	101/370 - (27%)
Similarity:	176/370 - (47%)	Gaps:	43/370 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAFISKDFRSPGETWIKTDGGWER-------SKVLECGGKRKRHHSEGSSSY-----------QD 47
            |.|:.:|:||||::|:||..||:|       :.|.:......:.:...|.:|           |:
  Rat     1 MPFLGQDWRSPGQSWVKTADGWKRFLDEKSGTFVSDLSSYCNKENLFNSLNYDVAAKKRKKDIQN 65

  Fly    48 SDSSEEEAVMPPHYHITIRCTREIAGFNGLSEAVKRLDFRRSVRDRKRFHYICAFLLLVSNKGIA 112
            |.:..:........::....|:|..|:..|.||..||||..::.|.:||:|:...|.|::...:.
  Rat    66 SKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLT 130

  Fly   113 SLPGSAQRQLLQMVEEVASHVNDSQQHPNVLRGLALKLEHIVSQENQKCWGKP--LGSTYLWKEH 175
            ||.|.||:..:.::|:|...|.:.||:..::|.|...|...:....|:. ||.  :|:..:|...
  Rat   131 SLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRV-GKSVLVGNINMWVYR 194

  Fly   176 MATIKRIQRVASQIEIREPDPEAKPKLHELPEECVREIILCIADHRDLESAAEAWETMAKLVSEQ 240
            |.|....|:..:.|:|..|..:.. .:.:||......|:..::|.|||.|..:|...:..|..::
  Rat   195 METTLHWQQQLNSIQISRPAFKGL-TITDLPVCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDR 258

  Fly   241 RIWRELTRFHFNQRQIHTILDL-DKFKQMGEIKDWKQIYHQLRRTYGVNDDYQFAEVLALCRSCC 304
            .:|:.|.::||::|||...|.| ||    |:: |||::|.:|.|.|...:  |:...|.||:.|.
  Rat   259 LLWKRLCQYHFSERQIRKRLILSDK----GQL-DWKKMYFKLVRCYPRRE--QYGVTLQLCKHCH 316

  Fly   305 CLFWPSDGHPCIVDQSPDYKQRLEEAGGQLALAQPVPPAQFLKYF 349
            .|.|....|||..: :|:            :.:..:.|..|:..|
  Rat   317 ILSWKGTDHPCTAN-NPE------------SCSVSLSPQDFINLF 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11658	NP_648498.1	None
Fbxo32	NP_598205.1	Nuclear localization signal. /evidence=ECO:0000250	57..62		0/4 (0%)
		Nuclear export signal. /evidence=ECO:0000250	164..168		1/3 (33%)
		Elongin_A	<252..>297	CDD:284333	18/49 (37%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250	275..290		7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353310
Domainoid	1	1.000	133	1.000	Domainoid score	I4931
eggNOG	1	0.900	-	-		E1_KOG3926
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4502
OMA	1	1.010	-	-		QHG46083
OrthoDB	1	1.010	-	-		D280011at33208
OrthoFinder	1	1.000	-	-		FOG0002870
OrthoInspector	1	1.000	-	-		otm45045
orthoMCL	1	0.900	-	-		OOG6_108752
Panther	1	1.100	-	-	LDO	PTHR13123
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2229
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.810