Protein Alignment Dnai2 and LOC4576277

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_001237748.2
• Gene: LOC4576277 / 4576277
• VectorBaseID: AGAMI1_000491
• Length: 693
• Species: Anopheles gambiae
• Alignment Length: 541
• Identity: 122/541 - (22%)
• Similarity: 206/541 - (38%)
• Gaps: 120/541 - (22%)

  Fly     7 KERRSFGARVHFED---KDEVVFTENSNPELVKSYILK-------NPVDRVTQYAGQTSLSVANT 61
            |.||:..|.....|   |...|.||..:.:.|.|::..       |.::|.|:     .::||::
Mosquito   169 KARRTADAEAQTRDLPCKSRSVNTECIHRQDVASFVSNYDMYDTYNDLERHTK-----EINVADS 228

  Fly    62 ----ERATYKSTGITHNEGGWPKDINMHDPEQTVRYKRKIEKDENYITQVMNLTKPMEHYIHQNN 122
                |..||...|:        :||:           .::.::.|:....|.|.:.:
Mosquito   229 ASKLEITTYSREGM--------EDID-----------ERLNRNANFHLSSMILQRLL-------- 266

  Fly   123 AVNIYENY---FENLDPAPLPEPCKS--------RTVNVYRDPNPIKVPVKHLSWSPDGGIKMAV 176
            |.|:|...   |.|:.|   |:||:.        ..:..||....:..||...||.|..|..:|:
Mosquito   267 AGNVYREQQIRFRNMYP---PDPCREDIRYLYRLDVLWTYRTVETLGKPVASASWCPANGDIVAL 328

  Fly   177 SHCDMRFQGDKSNQKCN-SYIWEVENPNEPFLTLEPKVPCVCLEYNQKDPTSLVSGMYNGQVAAW 240
            ::......| ..::.|. .|:|.::||..|........|..|:.::::.|..|..|:|:|:|...
Mosquito   329 AYGIYGHTG-SDDRGCGFVYVWNIKNPVNPERRYRFDCPVTCVAFSRRTPQLLAVGLYDGRVQVR 392

  Fly   241 D-TRHGKLPVMISEREVCHRDPVNSVLWNNSKSGTEFFSGGSD------------------GQVL 286
            | |...:.|:.:|.|:   |.||...:|:  ....||.:.|.|                  ||.|
Mosquito   393 DITDTTQTPLAVSNRD---RFPVYQPIWD--LKWVEFDNEGKDEVIAVSQNGWVMKYTLTIGQYL 452

  Fly   287 WWDTRKLTEPLDRLLMDPVK--------------SDDQDLSRSYGISVLEYETTI----PTRFMA 333
                  |..||.||  |.|:              :|.|.:.....:.......||    ..::..
Mosquito   453 ------LPYPLLRL--DRVEGTPEGQTSTGTSAPADQQPVRVQSDLHPQALCVTIHPVQKDKYYI 509

  Fly   334 GTEMGMLFSCNRKGKTPTEKIQIRMMCHLGPVYAITRNPAFVKNFLTV-GDWCARIWSEDCRESS 397
            ||:.|.:..|:.  ..|.:.:.:..| |...::.:..:|...:.|||. |||..|||.|:..| .
Mosquito   510 GTDEGAVHWCSI--NDPFQHLGVLQM-HSRGIFCLEYSPWSPRIFLTCSGDWSIRIWIEELPE-P 570

  Fly   398 IIWTKSSSSMLTDGAWSYTKVSQFFITRMDGVLDTWDLLQQQNEPV--LTVKVCDEPLYCVRTNE 460
            |:...:..:.:....||.|..:........|| ..|||.::.::|.  .|:......|..||...
Mosquito   571 IVTLCTGFAPIQAAYWSPTNSTVIASVTRSGV-QLWDLKRRSSKPASETTLGSLTTALTVVRFTN 634

  Fly   461 NGKFVSCGSQLGATFLVEVSD 481
            .|:.:..|...|...:..:.|
Mosquito   635 CGRCLLVGDAEGKAHVCALED 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	69/296 (23%)
		WD40 repeat	215..254	CDD:293791	11/39 (28%)
		WD40 repeat	262..304	CDD:293791	14/59 (24%)
		WD40 repeat	318..355	CDD:293791	7/40 (18%)
		WD40 repeat	365..401	CDD:293791	13/36 (36%)
		WD40 repeat	408..433	CDD:293791	5/24 (21%)
		WD40 repeat	162..208	CDD:293791	12/46 (26%)
LOC4576277	XP_001237748.2	WD40	<294..650	CDD:441893	87/374 (23%)
		WD40 repeat	368..406	CDD:293791	10/37 (27%)
		WD40 repeat	416..489	CDD:293791	17/82 (21%)
		WD40 repeat	497..533	CDD:293791	7/37 (19%)
		WD40 repeat	538..574	CDD:293791	13/36 (36%)
		WD40 repeat	581..621	CDD:293791	10/40 (25%)
		WD40 repeat	627..664	CDD:293791	7/29 (24%)