Protein Alignment Dnai2 and Dync2i1

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001420922.1
• Gene: Dync2i1 / 314523
• RGDID: 1306493
• Length: 1037
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 105/644 - (16%)
• Similarity: 190/644 - (29%)
• Gaps: 241/644 - (37%)

  Fly     4 IFKKERRSFGARVHFEDKDE-----------VVFTENSNPELVKSYILKN--------------- 42
            :|:|:.|:...:..:.|.::           |.|...|:.:..:|..||.
  Rat   418 MFQKQGRAENTKEPWADANDSTSRTPVCGIFVDFATASHRQKSRSQALKQKTRSTKLLRLIDLDF 482

  Fly    43 ----------PVDRVTQYAGQTSLSVANTERATYKSTGITHNEGGWPKDI-----------NMHD 86
                      ||:....|       :.|..:...|...:.:||....:||           ..|.
  Rat   483 SFTFSLLDLPPVNEYDMY-------IRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHP 540

  Fly    87 PEQTVRYKRKIEKDENYITQVMNLTKP-MEHYIH-------------------------QNNAVN 125
            .|.||......|||.:.:|.|..:..| :.:::.                         |:.|:|
  Rat   541 GEGTVVSGGSEEKDFSDVTVVPKIDTPRLSNFLRAACQVVAVLLEEDRLAAGPSWIPRAQDKALN 605

  Fly   126 IYENYFENLDPAPLPEPCKSRTVNVYRDPNPIKVPVKHLSWSPDGGIKMAVSHCDMRFQGDKSNQ 190
            |.::..:.....|..:..|...::..|......|.|..|   |:.....::         |..:.
  Rat   606 ISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDL---PEKAFAPSL---------DSRHL 658

  Fly   191 KCNSYIWEVENPNEP--FLTLEPKVPCVCLEYNQKDPTSLVSGMYNGQVAAWDTRHG-------- 245
            .|   :|::..|:.|  .|..|.||.|.|  ::......|.:|..:|.|..||.|..
  Rat   659 LC---VWDIWQPSGPQKVLICESKVTCCC--FSPLKAFLLFAGTVHGSVVVWDLREDSRIHHYVR 718

  Fly   246 --------KLPVMISE---REVCHRDPVNSV---------------------------------- 265
                    :.|...::   ..|.||.|:.::
  Rat   719 LSSCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMAGLSFHIASL 783

  Fly   266 -------LW----------NNSKSGTEFFSGG------------------SDGQVLWWDTRKLTE 295
                   :|          :.|.|......||                  .||: ||..|:.|:
  Rat   784 DESGVLNVWVVVELPKADISGSMSDLGLIPGGRIKLVHSTVIQLGHSLSHKDGE-LWGSTQTLS- 846

  Fly   296 PLDRLLMDPVKSDDQDLSRSYGISVLEYETTIPTRFMAGTEMGMLFSCNRKGKTPTEKIQIRMMC 360
                                     :::..:.|..|:.||:||::....|:....:.|:......
  Rat   847 -------------------------VKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPKVFKPQQH 886

  Fly   361 HLGPVYAITRNPAFVKNFLTVGDWCARIWSEDCRESSI------------IWTKSSSS-MLTDGA 412
            .:.|:..         |.:....:...::...|.:.||            .|..|:|. .:|...
  Rat   887 GVRPIKV---------NVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGRSVTSLQ 942

  Fly   413 WSYTKVSQFFITRMDGVLDTWDLLQQQNEPVLTVKVCDEPLYCVR-----TNENGKFVS 466
            ||.|:.:.|.:......:..||||:....||....:..:.|..:.     ...:|.||:
  Rat   943 WSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVA 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	58/361 (16%)
		WD40 repeat	215..254	CDD:293791	10/57 (18%)
		WD40 repeat	262..304	CDD:293791	11/110 (10%)
		WD40 repeat	318..355	CDD:293791	8/36 (22%)
		WD40 repeat	365..401	CDD:293791	4/47 (9%)
		WD40 repeat	408..433	CDD:293791	5/24 (21%)
		WD40 repeat	162..208	CDD:293791	7/47 (15%)
Dync2i1	NP_001420922.1	PTZ00121	<90..430	CDD:173412	3/11 (27%)
		WD40	580..965	CDD:441893	67/437 (15%)
		WD40 repeat	680..709	CDD:293791	9/30 (30%)
		WD40 repeat	714..757	CDD:293791	5/42 (12%)
		WD40 repeat	762..803	CDD:293791	1/40 (3%)
		WD40 repeat	844..885	CDD:293791	9/66 (14%)
		WD40 repeat	893..926	CDD:293791	4/41 (10%)
		WD40 repeat	938..963	CDD:293791	5/24 (21%)