Protein Alignment Dnai2 and wdr-60

DIOPT Version :9

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001367569.1
• Gene: wdr-60 / 175676
• WormBaseID: WBGene00016165
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 126/613 - (20%)
• Similarity: 201/613 - (32%)
• Gaps: 196/613 - (31%)

  Fly     7 KERRSFG------ARVHFEDKDEVVFTE---------NSNPELVKSYILKNPVDRVTQYAGQTSL 56
            :|:|:||      ..:..|.....|||:         ||.|        .|....:||.......
 Worm   150 QEQRAFGRLNKLRGLISIEVTKSQVFTDLSSNIFEPFNSLP--------SNKSHALTQTGKDCHT 206

  Fly    57 SVANTER--ATYKSTGITHNEG-----GWPKDINMHD----------PEQTVR-----YKRKIEK 99
            ....|||  ...|.|...|:|.     |..|:....|          ..||:|     ..:..|:
 Worm   207 EEVQTERGETEEKETQCPHSESTRIEDGIEKERTSTDRARLKKFFFAATQTIREILISEDKSAEE 271

  Fly   100 DEN---------------YITQVMNLTKPMEHYIHQNNAVNIYENYFENLDPAPLPEPC-KSRTV 148
            ||.               .:.||:..:|.......::::|.:....||    :|.|:.. ||..|
 Worm   272 DETREKSISKFSRGYNPFRLCQVVTKSKSTCIRKGESDSVLVAYEIFE----SPAPDLINKSLIV 332

  Fly   149 NVY----RDPNPIKVPVKHLSWSPDGGIKMAVSHCDMRFQGDKSNQKCNSYIWEVENPNEPFLTL 209
            ..:    |.|..:.|            ::..||..::    .:|:|
 Worm   333 EFFVHKRRPPKRLFV------------VESIVSVMEL----SQSSQ------------------- 362

  Fly   210 EPKVPCVCLEYNQKDPTSLVSGMYNGQVAAWDTR------HGKLPVMISEREVCHR--------- 259
               :..|||              .:|...|:|..      ...||.:.||..:..|
 Worm   363 ---ILYVCL--------------MDGTFCAFDLSITDAFFDDNLPWVDSETNIALRRPTFDSSFL 410

  Fly   260 -------DPVNSVLWNNSKSGTEFFSGGSDGQVLWWDTRKLTEPLDRLLMDPVKSDDQDLSR--- 314
                   .|:..:....|..|.|..:..:.|.:.:|...::.:...|||:..|......|.|
 Worm   411 ATTVSDATPLIGIALGKSSVGEEITTIDTAGTISYWIANRVEKNELRLLLTAVIRPHPVLKRHST 475

  Fly   315 SYGISVLEYETTIPTRFMAGTEMGMLFSCNRKG---------KTPTEKIQIRMMCHLGPVYAITR 370
            |:.:|...:.|. |.||..||:.|||:|..:..         ||..||        .|.|..|..
 Worm   476 SFAVSAFCHVTN-PLRFFIGTDTGMLYSMYKSDTSQAIPKIYKTEKEK--------YGEVTVIAA 531

  Fly   371 NPA--------FVKNFLTVGDWCARIWSEDCRESSI--IWTKSSSSMLTDGAWSYTKVSQFFITR 425
            ||:        |....::|        ....:.|||  |.|...|:.:|..:||.|..|.|:...
 Worm   532 NPSDNTVLIVGFSNGSISV--------YRTTQASSIVNIPTADLSTRVTWISWSLTNPSGFYTIH 588

  Fly   426 MDGVLDTWDLLQQQNEPVLTVKVCDEPLYCVRTNENGKFVSCGSQLG-ATFLVEVSDNMVMSAKN 489
            ...::..|||..:     |:.|..|.....|:...:..::|..:::| ..|.:...|:.|...::
 Worm   589 NSNIITYWDLGFK-----LSPKSVDHRTDSVQVLASDTWLSENAKIGYMAFGLSNGDSEVHVLED 648

  Fly   490 DKPLLTAMFERENRREKILEAKSRESKL 517
            .        .|:|:.|.|||...|...|
 Worm   649 P--------ARKNQNETILEVLRRIKNL 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	<160..482	CDD:225201	72/366 (20%)
		WD40 repeat	162..208	CDD:293791	4/45 (9%)
		WD40	212..469	CDD:295369	66/300 (22%)
		WD40 repeat	215..254	CDD:293791	9/44 (20%)
		WD40 repeat	262..304	CDD:293791	8/41 (20%)
		WD40 repeat	318..355	CDD:293791	15/45 (33%)
		WD40 repeat	365..401	CDD:293791	10/45 (22%)
		WD40 repeat	408..433	CDD:293791	6/24 (25%)
wdr-60	NP_001367569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900