Protein Alignment Dnai2 and dnai3

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001429749.1
• Gene: dnai3 / 100333131
• ZFINID: ZDB-GENE-121116-5
• Length: 890
• Species: Danio rerio
• Alignment Length: 661
• Identity: 138/661 - (20%)
• Similarity: 246/661 - (37%)
• Gaps: 164/661 - (24%)

  Fly     9 RRSFGARVHFEDKDEVVFTENSNPELVK--SYILKNPVDRVTQYAGQTSLSVANTER--ATYKST 69
            ||| |.||.|.|::.:.:.|    |||:  ||..|             |.|:...||  :|....
Zfish   198 RRS-GTRVRFSDRNALDWKE----ELVECSSYEDK-------------SFSITRMERDSSTQTCR 244

  Fly    70 GITH--NEGGWPKDINM---HDP----EQTVRYKRKIEKDENYITQVMNLTKPMEHYIHQNNAVN 125
            ..||  .:..|.|..||   ::|    .:..:::.:.|..:|:||.|   .:..|.|:.||...:
Zfish   245 DNTHTCTQTLWKKPKNMWSQYEPREFSSEEKQHQLQSENLKNFITSV---ARRFEIYLQQNLIAD 306

  Fly   126 IYENYFENL--DPAPLPEPCKSRTVNVYRDPNPI----KVPVKHLSWSPDGGIKMAVS---HCDM 181
            ::.:.:..|  |.|.|....::: :..|:....:    :..:.|:.|.|.....:.||   ...:
Zfish   307 VFCDDWTALCEDDASLMGKTETQ-LKEYQSFMDLHFSKEKTISHVQWHPSISGVIVVSMMERLSL 370

  Fly   182 RFQGDKSNQ----KCNSYIWEVENPNEPFLTLEPKVPCVCLEYNQKDPTSLVSGMYNGQVAAW-- 240
            ..:.|.|.:    ..:...|...:|..|.|.||.....:|.:::..|...:..|..||||..|
Zfish   371 EERIDSSTKLLLNPSHILFWSFSDPINPQLQLECPDDVLCFQFSPSDHNIIAGGCMNGQVVLWDI 435

  Fly   241 --------DTRHG------KL------PVM----ISEREVCHRDPVNSVLW-------------- 267
                    |||.|      ||      ||:    :|..|..|:.|:..:.|
Zfish   436 SAHVDRLQDTRSGGKNILNKLGKSDATPVVRYCAVSGIENGHKAPITDIQWLPETFEVNKLGTPV 500

  Fly   268 -NNSKSGTEFFSGGSDGQVLWWDTRKLTEPLDRLLMDPVKSDDQDLSRSYGI------------- 318
             |.|::..:..:...|..||:||.|.....:..|.....|.:::.|...:|:
Zfish   501 ENQSRTSVQLVTCAPDCCVLFWDLRAPRVMVHSLTDIKQKQEEKPLENPHGVPNTFTHLNLTWKP 565

  Fly   319 ------------------------SVLEYET----------------------------TIPTRF 331
                                    :.::|.|                            .|.|:.
Zfish   566 FIRVSLPKISSSGEYSPLKFSMRENTVDYNTGDKSVSGADSHVFAQLRMQSAKQQKPLQNISTKL 630

  Fly   332 MAGTEMGMLF-------SCNRKGKTPTEKIQIRMMCHLGPVYAITRNPAFVKNFLTVGDWCARIW 389
            ...||.|.|.       ..|..|:..:.|.....:.....::.::|:|.|....||||.:...||
Zfish   631 YIATEDGELVYTDWKVEKDNDSGRMLSAKPLDVFLLQDTLLHTVSRSPFFRDIILTVGRFSFSIW 695

  Fly   390 SEDCRESSIIWTKSSSSMLTDGAWSYTKVSQFFITRMDGVLDTWDLLQQQNEPVLTVKVCDEPLY 454
            .|......::.:..|.||.:.|.||.::.:..|:.|.||.::.|||||...:|..|..:....:.
Zfish   696 REGLTCGPLLMSVYSKSMFSAGHWSRSRPAVLFMGREDGDVEVWDLLQNSRQPSHTQNISTAAIS 760

  Fly   455 CVRTNENG---KFVSCGSQLGATFLVEVSDNMVMSAKNDKPLLTAMFERENRREKILEAKSRESK 516
            .:||..:.   ..::...:||...::::..::..|:.:::..:...||:|..|.:..|.:..:.:
Zfish   761 SIRTQTSSAKQNLLAVSDRLGTLHILQIPGSLRRSSSSERQNVEKYFEKEEERLQYFEKRQSDHQ 825

  Fly   517 LKVKANHGQDQ 527
            .|.|....:.|
Zfish   826 KKKKETEAEQQ 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	73/372 (20%)
		WD40 repeat	215..254	CDD:293791	17/64 (27%)
		WD40 repeat	262..304	CDD:293791	10/56 (18%)
		WD40 repeat	318..355	CDD:293791	11/108 (10%)
		WD40 repeat	365..401	CDD:293791	10/35 (29%)
		WD40 repeat	408..433	CDD:293791	7/24 (29%)
		WD40 repeat	162..208	CDD:293791	10/52 (19%)
dnai3	NP_001429749.1	None