Protein Alignment Dph1 and DPH2

DIOPT Version :9

• Sequence 1: NP_001261722.1
• Gene: Dph1 / 39317
• FlyBaseID: FBgn0036194
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_012730.1
• Gene: DPH2 / 853643
• SGDID: S000001674
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 444
• Identity: 97/444 - (21%)
• Similarity: 168/444 - (37%)
• Gaps: 123/444 - (27%)

  Fly    77 KRVALQLPEGLLMYAMVISDIVE-RFTSADTV--IMGDVTYGACCVDDYTAKALGADLLVHYGHS 138
            :.|.||.|:.|:..:.:|..::: :|......  ::.|..|.|||||:..|:.:.|:::||:|.:
Yeast    63 QNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTAYSACCVDEVAAEHVHAEVVVHFGDA 127

  Fly   139 CLIPVDQTCGIKVLYIFVDIKIDPLHFLDSVKLNFRPEVGQIALVSTIQFVTTLQAASTELKAAG 203
            ||..:.   .:.|:|.|....:|....:::.:..|.....:|.|::...|...|......||...
Yeast   128 CLNAIQ---NLPVVYSFGTPFLDLALVVENFQRAFPDLSSKICLMANAPFSKHLSQLYNILKGDL 189

  Fly   204 Y--DVI---------------------VPQ--------------------AKPLSPGE--ILGCT 223
            :  ::|                     ||:                    |..:||.:  :...|
Yeast   190 HYTNIIYSQVNTSAVEEKFVTILDTFHVPEDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLT 254

  Fly   224 SPQLPETTKMIIYLGDGRFHLESAMIANPLLKAYKYDPYEKKFTTEQYDHSAMQNLRLDAVQRAK 288
            :||.|.    ::||..   ..:|..|.:|.|......|:.......:|.|.            |:
Yeast   255 TPQDPR----LLYLST---VFQSVHIFDPALPGMVTGPFPSLMRRYKYMHV------------AR 300

  Fly   289 KARRIGIILGTLGRQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALFADIDAFVQIACPR- 352
            .|..|||::.||..:.:......|.|.:..:..:....::.:....|||.|.|||.:..:.|.:
Yeast   301 TAGCIGILVNTLSLRNTRETINELVKLIKTREKKHYLFVVGKPNVAKLANFEDIDIWCILGCSQS 365

  Fly   353 -LSIDWGSAFSQPLLNPYELSVVLG-DVEWTPHNSSPRNNAYPMDFYASGSLGPWTPNFKPPAIG 415
             :.:|..:.|.:|::.||||::.|. :|.||                     |.|..:|: .||.
Yeast   366 GIIVDQFNEFYKPIITPYELNLALSEEVTWT---------------------GKWVVDFR-DAID 408

  Fly   416 ECE---------------NKPSADCC-GR----------CTRAELE--KDDSGK 441
            |.|               ::|..|.. ||          .|..|||  .||..|
Yeast   409 EIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTHLELEAADDDDSK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph1	NP_001261722.1	Diphthamide_syn	83..380	CDD:280107	74/347 (21%)
DPH2	NP_012730.1	DPH2	11..524	CDD:272990	97/444 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810