DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dph1 and AT5G62030

DIOPT Version :9

Sequence 1:	NP_001261722.1	Gene:	Dph1 / 39317	FlyBaseID:	FBgn0036194	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_201009.1	Gene:	AT5G62030 / 836323	AraportID:	AT5G62030	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	425	Identity:	198/425 - (46%)
Similarity:	277/425 - (65%)	Gaps:	48/425 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PKKVFKPKARINRIPQELLDDPLLQQAIDRLPSNYNFEMHKTIWRIREMKAKRVALQLPEGLLMY 90
            ||:..|     |:||..:|.|..|..||..|||.|:||:||.:|||:...|||:|||||||||||
plant    18 PKRFIK-----NQIPDSILGDASLNAAISILPSIYHFEVHKCVWRIKTSNAKRIALQLPEGLLMY 77

  Fly    91 AMVISDIVERFTSAD-TVIMGDVTYGACCVDDYTAKALGADLLVHYGHSCLIPVDQTCGIKVLYI 154
            |:.:|||...|..|. ..::||||||||||||::|.|||||||:|||||||:|:|.| .|..||:
plant    78 ALTLSDIFTSFAGASHCFVLGDVTYGACCVDDFSACALGADLLIHYGHSCLVPIDST-KIPCLYV 141

  Fly   155 FVDIKIDPLHFLDSVKLNFRPEVGQIALVSTIQFVTTLQAASTELKAAGYDVIVPQAKPLSPGEI 219
            ||:|:||....|:::.||...:|..|.|..||||.:.::|...||:..|::|::||:||||.||:
plant   142 FVEIQIDVKCLLNTIHLNLASDVKNIILAGTIQFTSAIRAVKPELEKQGFNVLIPQSKPLSAGEV 206

  Fly   220 LGCTSPQLPET----TKMIIYLGDGRFHLESAMIANPLLKAYKYDPYEKKFTTEQYDHSAMQNLR 280
            ||||:|::...    .::::::.|||||||:.|||||.:||::||||..|...|:|||..|:..|
plant   207 LGCTAPKVKTVEDCKDQVLVFVADGRFHLEAFMIANPKIKAFRYDPYLGKLFLEEYDHKGMRETR 271

  Fly   281 LDAVQRAKKARRIGIILGTLGRQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALFAD-IDA 344
            :.|:.||::|:..||:||||||||:.::...|||::..|||::|.:|:||:.|.::|||.| :||
plant   272 MRAIARAREAKTWGIVLGTLGRQGNPKILERLEKKMMEKGIDSTVVLMSELSPTRVALFEDSVDA 336

  Fly   345 FVQIACPRLSIDWGSAFSQPLLNPYELSVVLGDVE-WTPHNSSPRNNA----------------- 391
            :|||||||||||||.||.:|||..:|..:.||.:. |..::||.|.|:
plant   337 WVQIACPRLSIDWGEAFLKPLLTTFEAEIALGFIRGWWENDSSSRVNSSSGCCKEDKETSCACKN 401

  Fly   392 -----------------YPMDFYASGSLGPWTPNF 409
                             ||||:||... |.|..::
plant   402 ENVKDDKKDNDGALDGDYPMDYYAQEG-GEWNSSY 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dph1	NP_001261722.1	Diphthamide_syn	83..380	CDD:280107	157/303 (52%)
AT5G62030	NP_201009.1	Diphthamide_syn	70..373	CDD:396438	157/303 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	326	1.000	Domainoid score	I268
eggNOG	1	0.900	-	-		E1_COG1736
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1059
Inparanoid	1	1.050	382	1.000	Inparanoid score	I528
OMA	1	1.010	-	-		QHG62277
OrthoDB	1	1.010	-	-		D750182at2759
OrthoFinder	1	1.000	-	-		FOG0003904
OrthoInspector	1	1.000	-	-		oto3433
orthoMCL	1	0.900	-	-		OOG6_101267
Panther	1	1.100	-	-	LDO	PTHR10762
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2688
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840