Protein Alignment Dph1 and dph-2

DIOPT Version :10

• Sequence 1: NP_648496.1
• Gene: Dph1 / 39317
• FlyBaseID: FBgn0036194
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001254257.1
• Gene: dph-2 / 174649
• WormBaseID: WBGene00007488
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 100/440 - (22%)
• Similarity: 181/440 - (41%)
• Gaps: 88/440 - (20%)

  Fly    54 DRLPSN---YNFEMHKTIWRIREMKAKRVALQLPEGLLMYAMVISDIVE-RFTSAD---TVIMGD 111
            :.||.|   ..||:..|...|::...:|:|||.|:.||.|:..::.::| ||.|..   |.::.|
 Worm    31 ENLPENDIHSFFEIDATSEWIKQGNHQRIALQFPDSLLPYSEKVTKLIESRFRSESAKKTFVLAD 95

  Fly   112 VTYGACCVDDYTAKALGADLLVHYGHSC-LIPVDQTCGIKVLYIFVDIKIDPLHFLDSVKLNFRP 175
            .:|.:||||:..|.......|||:|.:| ..|.|:   |.|.|:...:.|    |:|..::.|:.
 Worm    96 TSYRSCCVDEVAAAHADCTALVHFGEACHSAPTDK---IDVKYVLGSMPI----FIDQFRMEFQN 153

  Fly   176 EVGQIALVSTIQFVTTLQAASTELKAAGYDVIVPQAKPLSPGEILGCT---SPQLPETTKMIIYL 237
            ...|:.....:..:.:..:...|..||....::|..:.:.      |:   |..:.:..:..|||
 Worm   154 VADQLTAEHIVLLMDSCFSHEQEKVAAVIKEVLPGNRHVE------CSLLPSEDVLKQNRQNIYL 212

  Fly   238 GDGRFHLESAMIAN-------------PLLKAY-----------KYDPYEKKFTTEQYDHSAMQN 278
            |.   .:.|.:..|             |||..:           .::|..|....|....|.:..
 Worm   213 GR---EIPSCLRNNQPTDLIFCGFPNSPLLPIWLLSYPSCSTVSHFNPINKTIQHESTRSSRLLR 274

  Fly   279 LRLDAVQRAKKARRIGIILGTLG----RQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALF 339
            .||..|::.|.|..:|:::|::|    |:...|:....:|    .|.:...:.:.:|...||:.|
 Worm   275 KRLFLVEKLKDADTVGLVVGSVGVDKHREAVKRMREMCKK----AGKKIYVISVGKINVPKLSNF 335

  Fly   340 A-DIDAFVQIACPRLSIDWGSAFSQPLLNPYELSVVLGDVEWTPHNSSPRNNAYPMDFYASGSLG 403
            : |||.||.::||...:...|.:.:|:::.:|..:.|...:           .:..||
 Worm   336 STDIDVFVLLSCPFGVVLDSSDYFRPVVSYFEAEIALNPAK-----------TWAADF------- 382

  Fly   404 PWTPNFKPPAIGECENK-PSADCCG---------RCTRAELEKDDSGKAA 443
            .|:..|......:.|.: |.....|         |..:.|.||:..|.::
 Worm   383 GWSAEFAAFLEDKIETEVPDDKAAGDFSLISGKVRVQKTEEEKNGDGPSS 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph1	NP_648496.1	Diphthamide_syn	83..381	CDD:460365	77/334 (23%)
dph-2	NP_001254257.1	diphth2_R	6..476	CDD:473165	100/440 (23%)