Protein Alignment Dph1 and Dph1

DIOPT Version :10

• Sequence 1: NP_648496.1
• Gene: Dph1 / 39317
• FlyBaseID: FBgn0036194
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_652762.2
• Gene: Dph1 / 116905
• MGIID: 2151233
• Length: 438
• Species: Mus musculus
• Alignment Length: 439
• Identity: 239/439 - (54%)
• Similarity: 304/439 - (69%)
• Gaps: 37/439 - (8%)

  Fly    19 IVVVRARP-KKVFKPKARI------NRIPQELLDDPLLQQAIDRLPSNYNFEMHKTIWRIREMKA 76
            :|...|.| .:|...:.||      |:||.|:|::|.||.|:..||||||||:.||||||::.:|
Mouse     5 VVSETAEPGSRVGPGRGRISRGRLANQIPPEVLNNPQLQAAVQVLPSNYNFEIPKTIWRIQQAQA 69

  Fly    77 KRVALQLPEGLLMYAMVISDIVERFTSADTVIMGDVTYGACCVDDYTAKALGADLLVHYGHSCLI 141
            |:||||:|||||::|..|.||:||||.|:.::|||||||||||||:||:|||.|.|||||||||:
Mouse    70 KKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLV 134

  Fly   142 PVDQTC-GIKVLYIFVDIKIDPLHFLDSVKLNFRPEVGQIALVSTIQFVTTLQAASTELKAAGYD 205
            |:|.:. ..:|||:||||:||..|.||||:|.|.|. ..:|||||||||:|||||:.||| |.|.
Mouse   135 PMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPG-SSLALVSTIQFVSTLQAAAQELK-ADYH 197

  Fly   206 VIVPQAKPLSPGEILGCTSPQLPETTKMIIYLGDGRFHLESAMIANPLLKAYKYDPYEKKFTTEQ 270
            :.|||.||||||||||||||:|.:..:.::|||||||||||.|||||.:.||:||||.|..:.|.
Mouse   198 ISVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFHLESVMIANPNIPAYRYDPYGKVLSREY 262

  Fly   271 YDHSAMQNLRLDAVQRAKKARRIGIILGTLGRQGSSRVHRFLEKRLHAKGIETTTLLLSEIFPQK 335
            |||..||..|.:|:..|:.|:..|:||||||||||.::...||.:|...|:....||||||||.|
Mouse   263 YDHQRMQATRQEAIAAARSAKSWGLILGTLGRQGSPKILEHLESQLRNLGLPFVRLLLSEIFPSK 327

  Fly   336 LALFADIDAFVQIACPRLSIDWGSAFSQPLLNPYELSVVLGDVEWTPHNSSPRNNAYPMDFYASG 400
            |:|..::|.:||:|||||||||||||.:|||.|||.:|.|.|:.|        ...||||||:..
Mouse   328 LSLLPEVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKDISW--------QQPYPMDFYSGS 384

  Fly   401 SLGPWTPNF---KPPAIGECENKPSAD-------------CCGRCTRAE 433
            ||||||.|:   :.|. |.|:  |::|             .|..|..|:
Mouse   385 SLGPWTVNYGRDRAPR-GLCQ--PASDKVQQGSRGGSPAPACESCNCAD 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph1	NP_648496.1	Diphthamide_syn	83..381	CDD:460365	182/298 (61%)
Dph1	NP_652762.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		6/25 (24%)
		Diphthamide_syn	76..377	CDD:460365	178/301 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..438		6/31 (19%)