DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14135 and THAP7

DIOPT Version :9

Sequence 1:	NP_001261721.1	Gene:	CG14135 / 39316	FlyBaseID:	FBgn0036193	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001008695.1	Gene:	THAP7 / 80764	HGNCID:	23190	Length:	309	Species:	Homo sapiens

Alignment Length:	143	Identity:	35/143 - (24%)
Similarity:	61/143 - (42%)	Gaps:	29/143 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVKNCGNNNRIANRTKWRYFHFPKEKPNLQR--WIDFCQRDNINPTTACI----------CNEH 55
            |:...|...:....|.:...||...:|.|.:|  |:..|||  ::|:...:          |::|
Human     5 CSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQR--LDPSGQGLWDPASEYIYFCSKH 67

  Fly    56 FAPNDFERNMQYELGFSRKNPTKLKPGSFPSVNGPQKLAKELRGSIKRGSKSVPLAGSTKMSNIG 120
            |..:.||.     :|.|..:  :||.|:.|::.  :..:| ||.:.|....|.| .|..::|.:
Human    68 FEEDCFEL-----VGISGYH--RLKEGAVPTIF--ESFSK-LRRTTKTKGHSYP-PGPAEVSRL- 120

  Fly   121 FDPHHAGTQSSEG 133
               .....:.|||
Human   121 ---RRCRKRCSEG 130

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	24/96 (25%)
CG14135	NP_001261721.1	GrpE	198..>239	CDD:295646
THAP7	NP_001008695.1	THAP	4..93	CDD:214951	24/96 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	158..209
		HCFC1-binding motif (HBM). /evidence=ECO:0000250	229..232
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910