DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14135 and Thap1

DIOPT Version :9

Sequence 1:NP_001261721.1 Gene:CG14135 / 39316 FlyBaseID:FBgn0036193 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_950243.1 Gene:Thap1 / 73754 MGIID:1921004 Length:210 Species:Mus musculus


Alignment Length:256 Identity:53/256 - (20%)
Similarity:94/256 - (36%) Gaps:91/256 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CAVKNCGNNNRIANRTKWRYFH-FPKEKPNL-QRWIDFCQRDNINPTT-ACICNEHFAPNDFERN 64
            |:...|.|.   .::.|...|| ||..:|:| ::|....:|.|..||. :.||:|||.|:.|:|.
Mouse     5 CSAYGCKNR---YDKDKPVSFHKFPLTRPSLCKQWEAAVKRKNFKPTKYSSICSEHFTPDCFKRE 66

  Fly    65 MQYELGFSRKNPTKLKPGSFPSVNGPQKLAKELRGSIKRGSKSVPLAGSTKMSNIGFDPHHAGTQ 129
            ...:|         ||..:.|::                              .:..:||     
Mouse    67 CNNKL---------LKENAVPTI------------------------------FLYIEPH----- 87

  Fly   130 SSEGHETIEIQLCGFNTDIEGFEEAEDDDCPS-GPRLVEVE-----ILDPLNPQSNAK---DHVE 185
              |..|.:|.|                :..|| .|...:|:     ::.||....|..   ||..
Mouse    88 --EKKEDLESQ----------------EQLPSPSPPASQVDAAIGLLMPPLQTPDNLSVFCDHNY 134

  Fly   186 IIDSEGDSYVKHLELEICSLKREVFFLKDEYQKIKAEMRNLKDTIKRSEEELAEKQLQGVV 246
            .::.     ..|....|..|:::|       :|::.:::..:...:|.|.:|  ::|:.||
Mouse   135 TVED-----TMHQRKRILQLEQQV-------EKLRKKLKTAQQRCRRQERQL--EKLKEVV 181

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14135NP_001261721.1 THAP 2..88 CDD:283206 27/87 (31%)
GrpE 198..>239 CDD:295646 7/40 (18%)
Thap1NP_950243.1 THAP 4..82 CDD:214951 27/118 (23%)
HCFC1-binding motif (HBM). /evidence=ECO:0000250 131..134 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR46600
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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