DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14135 and Thap12

DIOPT Version :9

Sequence 1:	NP_001261721.1	Gene:	CG14135 / 39316	FlyBaseID:	FBgn0036193	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_082686.1	Gene:	Thap12 / 72981	MGIID:	1920231	Length:	758	Species:	Mus musculus

Alignment Length:	267	Identity:	54/267 - (20%)
Similarity:	95/267 - (35%)	Gaps:	85/267 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVKNCGNNNRIANRTKWRYFHFPKEKPNLQRWIDFCQRDNINPTTACICNEHF--APNDFERNM 65
            ||..||   .|.:.::...:|.||::....|:|::.|:|.::...|....|:|:  ....||.:|
Mouse     5 CAAPNC---TRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAKHFETSM 66

  Fly    66 QYELGFSRKNP--TKLKPGSFPSV-------NGP----QKLAKELRGSIKRGSKSVPLAGSTKMS 117
                 ..|.:|  |.|:..:.|::       |.|    :|..|||.....|..|...:..:
Mouse    67 -----ICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIEET---- 122

  Fly   118 NIGFDPHHAGTQSSEGHETIEIQLCGFNTDIEGFEEAEDDDCPSGPRLVEVEILDPLNPQSNAKD 182
                        |.:..||        ||:.:.         ||.         :.:|.|.....
Mouse   123 ------------SEQEQET--------NTNAQN---------PSA---------EAVNQQDANVL 149

  Fly   183 HVEIIDSEGDSYVKHL-ELEICSLKREV-------------FFLKDEYQKIKAEMRNLKDTIKRS 233
            .:.:.:.|...|:|.| |:.:...|:.:             .|..|.:|.:      |:..|...
Mouse   150 PLTLEEKENKEYLKSLFEILVLMGKQNIPLDGHEADEVPEGLFAPDNFQAL------LECRINSG 208

  Fly   234 EEELAEK 240
            ||.|.::
Mouse   209 EEVLRKR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	23/95 (24%)
CG14135	NP_001261721.1	GrpE	198..>239	CDD:295646	11/54 (20%)
Thap12	NP_082686.1	THAP	5..86	CDD:368467	23/88 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..141		7/66 (11%)
		DUF4371	152..326	CDD:372998	14/70 (20%)
		Dimer_Tnp_hAT	<669..726	CDD:368565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910