DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14135 and Thap3

DIOPT Version :9

Sequence 1:NP_001261721.1 Gene:CG14135 / 39316 FlyBaseID:FBgn0036193 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_780361.2 Gene:Thap3 / 69876 MGIID:1917126 Length:218 Species:Mus musculus


Alignment Length:237 Identity:58/237 - (24%)
Similarity:95/237 - (40%) Gaps:52/237 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CAVKNCGNNNRIANRTKWRYFH-FPKEKPNLQR-WIDFCQRDNINPTT-ACICNEHFAPNDFERN 64
            ||.:.|  .||.::|.|...|| ||..:|.|.| |:....|.:..|.. ..||:|||.|..|.  
Mouse     5 CAARQC--CNRYSSRRKQLTFHRFPFSRPELLREWVLNIGRADFKPKQHTVICSEHFRPECFS-- 65

  Fly    65 MQYELGFSRKNPTKLKPGSFPSV---NGPQKLAKELRGSIKRGSKSVPLAGSTKMSNIGFDPHHA 126
               ..| :|||   ||..:.|:|   ..|.::..|           |...|.:...|:.......
Mouse    66 ---AFG-NRKN---LKHNAVPTVFAFQNPTEVCPE-----------VGAGGDSSGRNMDTTLEEL 112

  Fly   127 GTQSSEGHETIEIQLCGFNTDIEGFEEAEDDDCPSGPRLVEVEILDPLNPQSNAKDHVEIIDSEG 191
            ...:.||  .::..|    .|.|..|..|....|:.|    :.:..||..|.:  ||        
Mouse   113 QPPTPEG--PVQQVL----PDREAMEATEAAGLPASP----LGLKRPLPGQPS--DH-------- 157

  Fly   192 DSYVKHLELEICSLKREVFFLKDEYQKIKAEMRNLKDTIKRS 233
             ||...   ::.:||:::|....|.::::..::..:..::|:
Mouse   158 -SYALS---DLDTLKKKLFLTLKENKRLRKRLKAQRLLLRRT 195

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14135NP_001261721.1 THAP 2..88 CDD:283206 32/90 (36%)
GrpE 198..>239 CDD:295646 5/36 (14%)
Thap3NP_780361.2 THAP 4..82 CDD:283206 31/87 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 97..120 4/24 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..154 5/24 (21%)
HCFC1-binding motif (HBM). /evidence=ECO:0000250 156..159 2/11 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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