Protein Alignment CG14135 and THAP1

DIOPT Version :9

• Sequence 1: NP_001261721.1
• Gene: CG14135 / 39316
• FlyBaseID: FBgn0036193
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_060575.1
• Gene: THAP1 / 55145
• HGNCID: 20856
• Length: 213
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 51/259 - (19%)
• Similarity: 92/259 - (35%)
• Gaps: 86/259 - (33%)

  Fly     3 CAVKNCGNNNRIANRTKWRYFH-FPKEKPNL-QRWIDFCQRDNINPTT-ACICNEHFAPNDFERN 64
            |:...|.|.   .::.|...|| ||..:|:| :.|....:|.|..||. :.||:|||.|:.|:|.
Human     5 CSAYGCKNR---YDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPDCFKRE 66

  Fly    65 MQYELGFSRKNPTKLKPGSFPSVNGPQKLAKELRGSIKRGSKSVPLAGSTKMSNIGFDPHHAGTQ 129
            ...:|         ||..:.|::                              .:..:||.....
Human    67 CNNKL---------LKENAVPTI------------------------------FLCTEPHDKKED 92

  Fly   130 SSEGHETIEIQLCGFNTDIEGFEEAEDDDCPSGPRLVEVE-----ILDPLNPQSNAK---DHVEI 186
            ..|..|.:                   ...|..|.:.:|:     ::.||....|..   ||...
Human    93 LLEPQEQL-------------------PPPPLPPPVSQVDAAIGLLMPPLQTPVNLSVFCDHNYT 138

  Fly   187 IDSEGDSYVKHLELEICSLKREVFFLKDEYQKIKAEMRNLKDTIKRSEEELAEKQLQGVVKSRK 250
            ::.     ..|....|..|:::|       :|::.:::..:...:|.|.:|  ::|:.||..:|
Human   139 VED-----TMHQRKRIHQLEQQV-------EKLRKKLKTAQQRCRRQERQL--EKLKEVVHFQK 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	27/87 (31%)
		GrpE	198..>239	CDD:295646	7/40 (18%)
THAP1	NP_060575.1	THAP	5..81	CDD:368467	27/117 (23%)
		HCFC1-binding motif (HBM)	134..137		2/2 (100%)
		Involved in homodimer formation. /evidence=ECO:0000269|PubMed:28299530	139..185		10/59 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46600
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010