DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14135 and Thap12

DIOPT Version :9

Sequence 1:	NP_001261721.1	Gene:	CG14135 / 39316	FlyBaseID:	FBgn0036193	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001178559.1	Gene:	Thap12 / 308845	RGDID:	1309679	Length:	757	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	54/259 - (20%)
Similarity:	96/259 - (37%)	Gaps:	69/259 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVKNCGNNNRIANRTKWRYFHFPKEKPNLQRWIDFCQRDNINPTTACICNEHF--APNDFERNM 65
            ||..||   .|.:.::...:|.||::....|:|::.|:|.::...|....|:|:  ....||.:|
  Rat     5 CAAPNC---TRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAKHFETSM 66

  Fly    66 QYELGFSRKNP--TKLKPGSFPSV-------NGP----QKLAKELRGSIKRGSKSVPLAGSTKMS 117
                 ..|.:|  |.|:..:.|::       |.|    :|..|||.....|..|...:..:::..
  Rat    67 -----ICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIEETSEQE 126

  Fly   118 NIGFDPHHAGTQSSEGHETIEIQLCGFNTDIEG------FEEAEDDDCPSGPRLVEVEILDPLNP 176
            .        .|.|:..:.:.|:     ....:|      .||.|:.:....  |.|:.||
  Rat   127 Q--------ETNSNAQNPSAEV-----GNQQDGNVLPLTLEEKENKEYLKS--LFEILIL----- 171

  Fly   177 QSNAKDHVEIIDSEGDSYVKHLELEICSLKREVFFLKDEYQKIKAEMRNLKDTIKRSEEELAEK 240
              ..|.::.:...|.|...:.|            |..|.:|.:      |:..|...||.|.::
  Rat   172 --MGKQNIPLDGHEADEIPEGL------------FAPDNFQAL------LECRINSGEEVLRKR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	23/95 (24%)
CG14135	NP_001261721.1	GrpE	198..>239	CDD:295646	9/40 (23%)
Thap12	NP_001178559.1	THAP	6..86	CDD:398893	22/87 (25%)
		DUF4371	<153..326	CDD:405048	19/90 (21%)
		Dimer_Tnp_hAT	<668..725	CDD:399013
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910