DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14135 and AgaP_AGAP006428

DIOPT Version :9

Sequence 1:	NP_001261721.1	Gene:	CG14135 / 39316	FlyBaseID:	FBgn0036193	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	XP_316465.2	Gene:	AgaP_AGAP006428 / 1277039	VectorBaseID:	AGAP006428	Length:	1117	Species:	Anopheles gambiae

Alignment Length:	222	Identity:	47/222 - (21%)
Similarity:	70/222 - (31%)	Gaps:	74/222 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RCAVKNCGNNNRIANRTKWRYFHFPKEKPNLQRWIDFCQ-RDNINPTTAC-ICNEHFAPNDFERN 64
            :|.|..|.:::.........|...|......:.||..|. .|:...|.|. :|:.||...||:.
Mosquito     5 KCIVPECPSSSARPEDRGVTYHKIPYLDEMKRLWIVACHLPDDYFATKASNVCSRHFRRADFQE- 68

  Fly    65 MQYELGFSRKNPTKLKPGSFPSVNGPQKLAK---ELRGSIKRGSKSVPLAGSTKMSNIGFDPHHA 126
                  |..|... ||.|..|:| .|..:.|   |...|.|...|..|                .
Mosquito    69 ------FKGKKYV-LKLGVVPTV-FPWTVTKPPGEAGSSTKSPQKPAP----------------K 109

  Fly   127 GTQSSEGHETIEIQLCGFNTDIEGFEEAEDDDCPSGPRLVEVEILDPLNPQSNAKDHVEIIDSEG 191
            |...::|.:.               ||.||.:.|.                       |:.|.:|
Mosquito   110 GKDDAKGAKV---------------EETEDGEVPH-----------------------EVGDMDG 136

  Fly   192 DSYVKHLELEICSLKREVFFLKDEYQK 218
            |..||. :.::.:|.:     .|:.||
Mosquito   137 DIVVKE-DAKVTALLK-----SDQAQK 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	22/87 (25%)
CG14135	NP_001261721.1	GrpE	198..>239	CDD:295646	4/21 (19%)
AgaP_AGAP006428	XP_316465.2	THAP	5..87	CDD:283206	23/90 (26%)
		Neuromodulin	93..275	CDD:284117	22/125 (18%)
		TEBP_beta	<137..238	CDD:254188	7/27 (26%)
		Agenet	249..304	CDD:283330
		TUDOR	312..361	CDD:197660
		MeCP2_MBD	456..530	CDD:238690
		PHD_SF	857..901	CDD:304600
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910