DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sugb and YHR140W

DIOPT Version :9

Sequence 1:	NP_648493.3	Gene:	Sugb / 39314	FlyBaseID:	FBgn0036191	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_012009.1	Gene:	YHR140W / 856543	SGDID:	S000001182	Length:	239	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	45/209 - (21%)
Similarity:	68/209 - (32%)	Gaps:	72/209 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 NVTLYCPKEKEYFKSNCTMDC----REDYLKEQ--LAESAVINTSSAVTMPQFW---LFFGLLIF 263
            |::.|      |.:.|..|:.    :.|::...  |..|.|:.:..|..   :|   |||..||.
Yeast    62 NISNY------YIQRNNKMNLETKKKSDFISRHVTLPVSLVLESIVATV---YWPLRLFFVNLIM 117

  Fly   264 SWIGMAVVVSIGDAICFGILGDRHHLYGKQRLCGSLGWGVFALLAGLLVDHMSLGEVNK----NY 324
            ..:...........:...|     |||.               :..||.||...|...|    |.
Yeast   118 HGVESTAKTPFPMTVDMAI-----HLYP---------------ILYLLADHYLSGSGTKFKLSNK 162

  Fly   325 TAVFWMALLIMGFDVFASSKLRHTPTHLSSNILKDVGQ------MFLSV----RCVIFFLWCVAI 379
            .|  |:.:..:.|..|         .:|:  .|.|.||      .||.|    :.:||.:  ||
Yeast   163 HA--WLIVTSLAFSYF---------QYLA--FLIDAGQGQAYPYPFLDVNEPYKSIIFVV--VA- 211

  Fly   380 GLGTALIWNFLFIY 393
                .:.|.:...|
Yeast   212 ----TITWAYYVFY 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sugb	NP_648493.3	MFS	9..82	CDD:304372
		MFS_1	16..>96	CDD:284993
		MFS_1	<252..518	CDD:284993	35/159 (22%)
		MFS	<254..547	CDD:119392	35/157 (22%)
YHR140W	NP_012009.1	Far-17a_AIG1	<83..220	CDD:368096	39/179 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950