DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sugb and GDS1

DIOPT Version :9

Sequence 1:	NP_648493.3	Gene:	Sugb / 39314	FlyBaseID:	FBgn0036191	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_015000.3	Gene:	GDS1 / 854537	SGDID:	S000005882	Length:	522	Species:	Saccharomyces cerevisiae

Alignment Length:	273	Identity:	50/273 - (18%)
Similarity:	82/273 - (30%)	Gaps:	90/273 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 ILPIIGMLAKPLFGYIADRYHRHRPLFLGGQVLTGIAFFLIMFVPGMEKPLPKVEFHCH---QGV 111
            ::|:.|...||        .:|..|  |...||.  |.|||::.....:....|:..|.   |..
Yeast    97 LIPVTGERPKP--------ENRDSP--LDDDVLH--AVFLILWEMDPNQQGMTVKQLCDLLLQKH 149

  Fly   112 SDIPRFCSEYGECVERNLERYY-----GNRTLECELNCEAQPFMWD-------------IVCEDW 158
            .|:....::....:...|..|.     |.:||...|:.|     |.             |:..|:
Yeast   150 PDMSNLSTKLSNLISAKLNAYVKKIEKGEKTLTYALSRE-----WSNSSPRRMLYIYRGILSPDY 209

  Fly   159 ----------LKNNTE----------------NCAANRTNTQMEFGASIT----------MQKIE 187
                      ||...|                ..::|:......:.:|:|          ..|..
Yeast   210 KEHAQAVTMQLKQQLETSGDTSDFNSNGKKKRESSSNQLVNNDSYSSSMTDMKNMSSNSSFSKNL 274

  Fly   188 NDGSCMF-----FMIPHDQGQI--------AGQNVTLYCPKEKEYFKSNCTMDCREDYLKEQLAE 239
            |.|:..|     |.||:....:        :.....|..|......|:|   :.:.:|:.|...|
Yeast   275 NVGNLAFSLSPEFNIPYSTSPVSLNLSPSMSNNQQQLLTPNSASKSKNN---NKKRNYMDEDTNE 336

  Fly   240 SAVINTSSAVTMP 252
            |......:..|.|
Yeast   337 SMTEPKKTKTTKP 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sugb	NP_648493.3	MFS	9..82	CDD:304372	7/31 (23%)
		MFS_1	16..>96	CDD:284993	13/45 (29%)
		MFS_1	<252..518	CDD:284993	1/1 (100%)
		MFS	<254..547	CDD:119392
GDS1	NP_015000.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950