Protein Alignment Sugb and GDH2

DIOPT Version :9

• Sequence 1: NP_648493.3
• Gene: Sugb / 39314
• FlyBaseID: FBgn0036191
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_010066.1
• Gene: GDH2 / 851311
• SGDID: S000002374
• Length: 1092
• Species: Saccharomyces cerevisiae
• Alignment Length: 614
• Identity: 117/614 - (19%)
• Similarity: 206/614 - (33%)
• Gaps: 195/614 - (31%)

  Fly   101 PKVEFHCHQGVSDIPRFCSEYG--------------------ECVERNLERYYGNRTLECELNCE 145
            ||...:.|.|...|..|.:..|                    |.|| ||:|...|.||..:....
Yeast   385 PKEAIYAHIGAIFINHFVNRLGSDYQNLLSQITIKRNDTTLLEIVE-NLKRKLRNETLTQQTIIN 448

  Fly   146 AQPFMWDIVCEDWLKNNTENCAANRTNTQMEFGASITMQKIE------NDGSCMFFM---IPHDQ 201
            .....:.|:.:.: ||..:....:.:...||  .:::.|::|      ||.....::   ||:|.
Yeast   449 IMSKHYTIISKLY-KNFAQIHYYHNSTKDME--KTLSFQRLEKVEPFKNDQEFEAYLNKFIPNDS 510

  Fly   202 GQ-IAGQNVTLYCPKEKEYFKSNCTMDCREDYLKEQLAESAVINTSSAVT---MPQ--FWLFF-- 258
            .. :..:.:.::   .|...|:|.       ::..::|.|..::.|..:|   .|:  :.:||
Yeast   511 PDLLILKTLNIF---NKSILKTNF-------FITRKVAISFRLDPSLVMTKFEYPETPYGIFFVV 565

  Fly   259 -----GLLI-FSWI---GMAVVVS----IGDAICFGILGDRHHLYGKQRL-------CGSLGWGV 303
                 |..| |..|   |:.:|.|    |.|.....::.:.:.|...|:.       .||.  ||
Yeast   566 GNTFKGFHIRFRDIARGGIRIVCSRNQDIYDLNSKNVIDENYQLASTQQRKNKDIPEGGSK--GV 628

  Fly   304 FALLAGL----------------LVDHMSLGEVNKNYTAVFWMALLIM--------GFDVFAS-- 342
            ..|..||                ::|.:....:.:||..:.....::.        ||..:|:
Yeast   629 ILLNPGLVEHDQTFVAFSQYVDAMIDILINDPLKENYVNLLPKEEILFFGPDEGTAGFVDWATNH 693

  Fly   343 SKLRHTP------THLSSNI----LKDVGQMFLSVRCVIFFLWCVAIGLGTALIWNFLF------ 391
            :::|:.|      |..|.::    ..:.|...|.||..:..:: ..:.|..:.::.|..
Yeast   694 ARVRNCPWWKSFLTGKSPSLGGIPHDEYGMTSLGVRAYVNKIY-ETLNLTNSTVYKFQTGGPDGD 757

  Fly   392 -------------IYLEELDKAFEGCDSSIKTLEGLVMGIQCFGGELPFFFLSGWILKKIGHVNA 443
                         .||..||.:...||.     :||.....|                ::.|...
Yeast   758 LGSNEILLSSPNECYLAILDGSGVLCDP-----KGLDKDELC----------------RLAHERK 801

  Fly   444 MSVVLFGFGVRFILYSMLQNPWYILPIELM-----------NGVTFGLFYAT----MASYASIVA 493
            |   :..|..     |.|.|..:.:.::.|           ||.||...:.|    ...:..|..
Yeast   802 M---ISDFDT-----SKLSNNGFFVSVDAMDIMLPNGTIVANGTTFRNTFHTQIFKFVDHVDIFV 858

  Fly   494 PPG---TDATMQSLVGAIFEGVG-VSMGSLIAG-QLFESVTARTTFEIFGIGAFIVFVIHVCIQL 553
            |.|   ...|:.:|...:.|..| ..:..::.| .||.:..|:...|           .|.|| |
Yeast   859 PCGGRPNSITLNNLHYFVDEKTGKCKIPYIVEGANLFITQPAKNALE-----------EHGCI-L 911

  Fly   554 YLQRNSNIDENGKGTVASASATASPSAPL 582
            :...::|     ||.|.|:|.....|..|
Yeast   912 FKDASAN-----KGGVTSSSMEVLASLAL 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sugb	NP_648493.3	MFS	9..82	CDD:304372
		MFS_1	16..>96	CDD:284993
		MFS_1	<252..518	CDD:284993	65/363 (18%)
		MFS	<254..547	CDD:119392	69/389 (18%)
GDH2	NP_010066.1	Bac_GDH	1..1092	CDD:421780	117/614 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950