DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sugb and SEC72

DIOPT Version :9

Sequence 1:	NP_648493.3	Gene:	Sugb / 39314	FlyBaseID:	FBgn0036191	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_013395.1	Gene:	SEC72 / 850999	SGDID:	S000004283	Length:	193	Species:	Saccharomyces cerevisiae

Alignment Length:	152	Identity:	30/152 - (19%)
Similarity:	53/152 - (34%)	Gaps:	49/152 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 VFALLAGLLVDHMS------LGEVNKNYTAVFWMALLIMGFDVFASSKLRHTPTHLSSNILKDVG 361
            |.||.....:|.::      :||.|.|:|.....||..|...:|.|. :::......:..||:|.
Yeast    19 VVALSTETNIDQINVLTTSLIGETNPNFTPQPNEALSKMIKGLFESG-MKNLQQKKLNEALKNVS 82

  Fly   362 ---------------------QMFLSVRCVIFFLWCVAIG------------LGTALIWNFLFI- 392
                                 ::...:|..|..  |:.:|            |||.||...:|:
Yeast    83 LAIEMAQRKRAPWEAFAIQLPELHFMLRSKIDL--CLILGKHLEALQDLDFLLGTGLIQPDVFVR 145

  Fly   393 ------YLEELDKAFEGCDSSI 408
                  .|.:.::|...|:..:
Yeast   146 KADCLLKLRQWEEARATCERGL 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sugb	NP_648493.3	MFS	9..82	CDD:304372
		MFS_1	16..>96	CDD:284993
		MFS_1	<252..518	CDD:284993	30/152 (20%)
		MFS	<254..547	CDD:119392	30/152 (20%)
SEC72	NP_013395.1	TPR repeat	139..169	CDD:276809	4/29 (14%)
SEC72	NP_013395.1	PLN03088	<143..>189	CDD:215568	4/25 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950