Protein Alignment TfIIEalpha and Gtf2e1

DIOPT Version :10

• Sequence 1: NP_524026.1
• Gene: TfIIEalpha / 39313
• FlyBaseID: FBgn0015828
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_083088.1
• Gene: Gtf2e1 / 74197
• MGIID: 1921447
• Length: 440
• Species: Mus musculus
• Alignment Length: 442
• Identity: 197/442 - (44%)
• Similarity: 272/442 - (61%)
• Gaps: 41/442 - (9%)

  Fly    21 VTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTLRTDKF 85
            :||||::||:||:.|:||||.:|..|.:|:|:||||:||:|:.|||:|::||||:.:..|:.|||
Mouse     7 LTEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKF 71

  Fly    86 IQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSSCSKTF 150
            |:.|:::||..|||..:.|||||||:|.|||||||||.||:|:||:||::|:||||||..|..||
Mouse    72 IKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTF 136

  Fly   151 TDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQPLYDLLREVEGIKLAP 215
            |||||:||||..|..||||||.:.||||.:||||||:|.:||.||||::|:|.||||.|.:.||.
Mouse   137 TDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAY 201

  Fly   216 EVLEPEPVDIDTIRGLNKPNATRPDGMAWSG----EATRNQGFAVEETRV-DVTIGGDDTSDAVI 275
            |:|||||.:|..::......||.......:|    ||..|:|.:.|:... :|.|..||..|  :
Mouse   202 EILEPEPTEIPALKQSKDRAATAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVINMDDQDD--V 264

  Fly   276 ER--------KSRPIWMTESTV---ITDTDAADGAADAVQTASGSGHRNRKE-------NEDIMS 322
            .|        |.||||:.||||   .:..:..:|..| |.|     .:.|:|       ||::|.
Mouse   265 HRPSLEGKAAKERPIWLRESTVQGAYSSEEMKEGGID-VDT-----FQEREEARAGPDDNEEVMR 323

  Fly   323 VLLQHEKQPGQKEPHMKGMRVGSSNANSSDSSDD--EKDIENSKIPDVDFDNYINSDSAEEDD-- 383
            .||.|||:.........|.....:.||.|||..:  |.|.::...|......:.:.|..|||:
Mouse   324 ALLIHEKKTSSVTAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAAAPPHHHRDEDEEDEEF 388

  Fly   384 ----DVPTVLVAGRPHPLDQLDD--NLIAQMTPQEKENYIHVYQQHYSHIFE 429
                |.|.|:|||.|....::..  .|:|||||:|||.||.:.|:.:..:||
Mouse   389 EEVADDPIVMVAGCPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIEalpha	NP_524026.1	TFIIE	43..188	CDD:128804	90/144 (63%)
		TFIIE-A_C	357..429	CDD:463287	26/79 (33%)
Gtf2e1	NP_083088.1	TFIIE	28..175	CDD:128804	90/146 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..395		14/61 (23%)
		TFIIE-A_C	<395..440	CDD:463287	18/44 (41%)