Protein Alignment TfIIEalpha and gtf2e1

DIOPT Version :10

• Sequence 1: NP_524026.1
• Gene: TfIIEalpha / 39313
• FlyBaseID: FBgn0015828
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001038610.1
• Gene: gtf2e1 / 567899
• ZFINID: ZDB-GENE-041210-221
• Length: 447
• Species: Danio rerio
• Alignment Length: 446
• Identity: 190/446 - (42%)
• Similarity: 273/446 - (61%)
• Gaps: 34/446 - (7%)

  Fly    16 TEVRYVTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTL 80
            ||...:||||:|||:||:.||||||.:|.||.:|:|:||||::|:|:.|||:|::||||:.:.||
Zfish     2 TEPELLTEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTL 66

  Fly    81 RTDKFIQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSS 145
            :.|||::.|:::||.||||..:.|||||||:..|||||||||.||:|:||:|||:|:||||:|..
Zfish    67 KADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPC 131

  Fly   146 CSKTFTDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQPLYDLLREVEG 210
            |:.|||||||:||||..|..||||||.:.||||.:|:||||:|.::|.||||::|:|.||||.|.
Zfish   132 CTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQIEPIYVLLRETEN 196

  Fly   211 IKLAPEVLEPEPVDIDTIRGLNKPNATRPDGMAWSGEATR---NQGFAVEETRVDVTIGGDDTSD 272
            |.|:.::|||||.:|..:: .::..|.:....|.:|...|   .:|.:.:....:|.|..:|...
Zfish   197 INLSHDLLEPEPSEIPALK-QSRERAAQTAAGAGAGGPVREVWKKGTSYDLYTQNVVINMEDQEP 260

  Fly   273 AVIER------KSRPIWMTESTV---ITDTDA-ADGAADAVQTASGSGHRN--RKENEDIMSVLL 325
            ...:.      |.||:|:|||||   ..:|:| .:...|:|.|..|...|.  :.|||::|..||
Zfish   261 QPGQNAEGKAPKERPVWLTESTVQGAYNETEALKNPGEDSVVTQEGITGRGAAQDENEEVMLALL 325

  Fly   326 QHEKQPGQKEPHMKGMRVGSSNANSSDSSDDEKDIENSKIPDV----------------DFDNYI 374
            .|||:.|.........|.....||:|||..|..:.:....|..                |.::..
Zfish   326 IHEKRSGAGPGGSAVSRPTVPAANASDSDSDTSESDEDSPPQAPAHTLHSTTSMRPGKQDEEDED 390

  Fly   375 NSDSAEEDDDVPTVLVAGRPHPLDQLDD--NLIAQMTPQEKENYIHVYQQHYSHIF 428
            :.|..||..|.|.|:|.|||....::..  .|:.||:.||||.||.:.|..:..::
Zfish   391 DDDEFEEVGDDPVVMVGGRPFSYREVSQRPELVEQMSAQEKEAYIEMGQNLFQDMY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIEalpha	NP_524026.1	TFIIE	43..188	CDD:128804	89/144 (62%)
		TFIIE-A_C	357..429	CDD:463287	22/90 (24%)
gtf2e1	NP_001038610.1	TFIIE	28..175	CDD:128804	89/146 (61%)
		TFIIE-A_C	<402..447	CDD:463287	16/45 (36%)