Protein Alignment TfIIEalpha and Gtf2e1

DIOPT Version :10

• Sequence 1: NP_524026.1
• Gene: TfIIEalpha / 39313
• FlyBaseID: FBgn0015828
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001094026.1
• Gene: Gtf2e1 / 303918
• RGDID: 1306851
• Length: 438
• Species: Rattus norvegicus
• Alignment Length: 442
• Identity: 195/442 - (44%)
• Similarity: 270/442 - (61%)
• Gaps: 43/442 - (9%)

  Fly    21 VTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTLRTDKF 85
            :||||::||:||:.|:||||.:|..|.:|:|:||||:||:|:.|||:|::||||:.:..|:.|||
  Rat     7 LTEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKF 71

  Fly    86 IQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSSCSKTF 150
            |:.|:::||..|||..:.|||||||:|.|||||||||.||:|:||:||::|:||||||..|..||
  Rat    72 IKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTF 136

  Fly   151 TDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQPLYDLLREVEGIKLAP 215
            |||||:|||:..|..||||||.:.||||.:||||||:|.:||.||||::|:|.||||.|.:.||.
  Rat   137 TDLEANQLFEPMTGTFRCTFCQAEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAY 201

  Fly   216 EVLEPEPVDIDTIRGLNKPNATRPDGMAWSG-----EATRNQGFAVEETRV-DVTIGGDDTSDAV 274
            |:|||||.:|..:: .:|..|....|.|...     ||..|:|.:.|:... :|.|..||..|
  Rat   202 EILEPEPTEIPALK-QSKDRAASAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVISMDDQDD-- 263

  Fly   275 IER--------KSRPIWMTESTVITDTDAADGAADAVQTASG----SGHRNRKE-------NEDI 320
            :.|        |.||||:.||||       .||..:.:...|    ...::|:|       ||::
  Rat   264 VHRTSLEGKAAKERPIWLRESTV-------QGAYGSEEMKEGGIDMDTFQDREEARAGPDDNEEV 321

  Fly   321 MSVLLQHEKQPGQKEPHMKGMRVGSSNANSSDSSDDEKDIENSKIPDVDFDNYINSDSAEEDD-- 383
            |..||.|||:.........|.....:.||.|||..:..:.::...|........:.|..||||
  Rat   322 MRALLIHEKKTSSATAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAAAPHHRDEDEEDDEF 386

  Fly   384 ----DVPTVLVAGRPHPLDQLDD--NLIAQMTPQEKENYIHVYQQHYSHIFE 429
                |.|.|:|||.|....::..  .|:|||||:|||.||.:.|:.:..:||
  Rat   387 EEVADDPVVMVAGCPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIEalpha	NP_524026.1	TFIIE	43..188	CDD:128804	89/144 (62%)
		TFIIE-A_C	357..429	CDD:463287	25/79 (32%)
Gtf2e1	NP_001094026.1	TFIIE	28..175	CDD:128804	89/146 (61%)
		TFIIE-A_C	<393..438	CDD:463287	18/44 (41%)