DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and AMN1

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_009716.1 Gene:AMN1 / 852455 SGDID:S000000362 Length:549 Species:Saccharomyces cerevisiae


Alignment Length:580 Identity:120/580 - (20%)
Similarity:196/580 - (33%) Gaps:184/580 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 TPTPAAPSGKTSVMERVTNALCG--GGN---SNSNSGSN---------SSNSNTSSASATAATSP 102
            :|:|:..|.|   ||:....:..  ||:   |:.|.||:         |..::.|...::..|:|
Yeast    33 SPSPSFTSLK---MEKPFKDIVRKYGGHLHQSSYNPGSSKVELVRPDLSLKTDQSFLQSSVQTTP 94

  Fly   103 ASN------ANPPQTPDK---------PSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQH 152
            ...      :.|..||.|         .||..|.|...|..|   ::::|.   |:.:..:.:..
Yeast    95 NKKSCNEYLSTPEATPLKNTATENAWATSRVVSASSLSIVTP---TEIKNI---LVDEFSELKLG 153

  Fly   153 MQL-QQSQQQHLQLQASTLINSNHHVMVGPAPPTGMPLGAPPTPTVKSIAKQMNITIPGGGV--- 213
            ..| .|.|:.|...:...::.:                      .:|.|....:..||....   
Yeast   154 QPLTAQHQRSHAVFEIPEIVEN----------------------IIKMIVSLESANIPKERPCLR 196

  Fly   214 -NPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMG------------INAASP 265
             ||.|...|.: |...::.|..|.....|||..   |.:.|.....|            :|...|
Yeast   197 RNPQSYEHSLL-MYKDEERAKKAWSAAQQLRDP---PLVGHKEKKQGALFSCMMVNRLWLNVTRP 257

  Fly   266 LIMQHQLHPPPIHSIE----------QLMLDDRF-LSRFFQYFSPYERRILAQVC--IKWRDTLY 317
            .:.: .||...:|:.:          |:|....| |.:..|...|...|:....|  :||.: .|
Yeast   258 FLFK-SLHFKSVHNFKEFLRTSQETTQVMRPSHFILHKLHQVTQPDIERLSRMECQNLKWLE-FY 320

  Fly   318 RSPRY-----WSGLLPTLQCRELRQMPGCDRGKLYNSLIRRGFHALGLVGASDEDALDVVHSFPL 377
            ..||.     |...|..|   |...:||                                     
Yeast   321 VCPRITPPLSWFDNLHKL---EKLIIPG------------------------------------- 345

  Fly   378 ASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLT---PRIVSLSLADC 439
                       ..:|.|..|..|...:.:|..|.|..|:.|:::|: .|:.   |::.:      
Yeast   346 -----------NKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGV-VCIALNCPKLKT------ 392

  Fly   440 INIADEAVGAVAQLLPSLYEFSLQAY-----------HVTDAALGYFSPKQSHSLSILRLQSCWE 493
            .||.....|   .|:.|:...:|..|           .|.||.:..|:.....::..|.|.||..
Yeast   393 FNIGRHRRG---NLITSVSLVALGKYTQVETVGFAGCDVDDAGIWEFARLNGKNVERLSLNSCRL 454

  Fly   494 LTNHG--IVNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQKLRALD----LSWCPRIT 547
            ||::.  |:..::|.|:|.||.:....|:||.. ..:..||.| ::||    :..|.|||
Yeast   455 LTDYSLPILFALNSFPNLAVLEIRNLDKITDVR-HFVKYNLWK-KSLDAPILIEACERIT 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 4/23 (17%)
AMN1 383..600 CDD:187754 47/185 (25%)
leucine-rich repeat 431..456 CDD:275381 4/24 (17%)
leucine-rich repeat 457..482 CDD:275381 6/35 (17%)
leucine-rich repeat 483..508 CDD:275381 8/26 (31%)
leucine-rich repeat 509..534 CDD:275381 8/24 (33%)
leucine-rich repeat 535..560 CDD:275381 6/17 (35%)
leucine-rich repeat 561..585 CDD:275381
leucine-rich repeat 586..610 CDD:275381
leucine-rich repeat 636..661 CDD:275381
AMN1NP_009716.1 AMN1 285..509 CDD:187754 61/287 (21%)
leucine-rich repeat 314..337 CDD:275381 7/23 (30%)
leucine-rich repeat 338..363 CDD:275381 8/75 (11%)
leucine-rich repeat 364..389 CDD:275381 7/25 (28%)
leucine-rich repeat 390..417 CDD:275381 7/35 (20%)
leucine-rich repeat 418..443 CDD:275381 4/24 (17%)
leucine-rich repeat 444..471 CDD:275381 8/26 (31%)
leucine-rich repeat 472..493 CDD:275381 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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