DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and AT2G17020

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_565400.1	Gene:	AT2G17020 / 816205	AraportID:	AT2G17020	Length:	656	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	118/481 - (24%)
Similarity:	188/481 - (39%)	Gaps:	103/481 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 PNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQLMLDDRFL--SRFFQYFSPYERRILAQVC 309
            ||.|:.:.  |:.:....||:..:|       .:..|.||...|  |.......|..|.|....|
plant    65 PNFHIFNV--SLSMETVRPLLFPNQ-------QLSSLKLDCGRLGNSAIDILVRPSLREISLHNC 120

  Fly   310 IKWRDTLYRSPRYWSG-LLPTL--QCRELRQM-PGCDRGKLYNSLIRRGFHALGLVGASDEDALD 370
                       |.:|| |:..:  :|::||.: .|....|:..|:.|.....| |.|.|..:.|.
plant   121 -----------RDFSGDLISEIGRKCKDLRLLCLGSVAEKVGRSISRCALEDL-LNGCSHLEVLA 173

  Fly   371 VVHSFPLASKHVHSLSLRCSS------ISDRGLETLLDHL------QSLFELELAG--CNEVTEA 421
            ::  |.|      ||.||...      :|||.....|.|:      |.|...|::|  .|.||.
plant   174 LM--FDL------SLYLRPGDGRIFGLVSDRLTHLELGHITSRMMTQLLTSTEISGQDSNRVTT- 229

  Fly   422 GLWACLTPRIVSLSLA-DCINIADEAVGAVAQLLPSLYEFSL---------QAYHVTDAALGYFS 476
               :.:...:..|.|: ||  |.|..|.|:::.||||.:..:         |...:||..|...:
plant   230 ---STVLQNVQRLRLSVDC--ITDAVVKAISKSLPSLIDLDIRDAPLEDPRQVSDLTDFGLHEIN 289

  Fly   477 P--KQSHSLSILRLQSCW-----ELTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQK 534
            .  |..| ||::|.|...     .:::.|::.:......:..:.|.|..::||.|.:.|..:...
plant   290 QNGKLKH-LSLIRSQEFHPTYFRRVSDQGMLFLADKCLGMETICLGGFCRVTDAGFKTILHSCAS 353

  Fly   535 LRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVRD 599
            |....:...|::||.....|......|..::|.||..:||..:..:::.|.|..|.||.|..:||
plant   354 LSKFSIYHGPKLTDLVFHDILATTLSLSHVSLRRCHLLTDHAIQKLASSLKLENLDLRGCRNLRD 418

  Fly   600 FGLQHLCSMRNLQV--------------------------LSLAGCPLLTSSGLSSLI---QLRH 635
            ..|..:..:..|:|                          ||:.||..||...:|:|.   ....
plant   419 ETLTAVSHLPKLKVLLLDGADISDTGLSYLKEGVLDSLVSLSVRGCRNLTDKFMSTLFDGSSKLA 483

  Fly   636 LQELELTNCPGASH-ELFDYLKEHLP 660
            |:||:|:|.|..:. .:|...|...|
plant   484 LRELDLSNLPNLTDAAIFALAKSGAP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	9/35 (26%)
		AMN1	383..600	CDD:187754	63/247 (26%)
		leucine-rich repeat	431..456	CDD:275381	9/25 (36%)
		leucine-rich repeat	457..482	CDD:275381	6/35 (17%)
		leucine-rich repeat	483..508	CDD:275381	5/29 (17%)
		leucine-rich repeat	509..534	CDD:275381	6/24 (25%)
		leucine-rich repeat	535..560	CDD:275381	5/24 (21%)
		leucine-rich repeat	561..585	CDD:275381	6/23 (26%)
		leucine-rich repeat	586..610	CDD:275381	8/23 (35%)
		leucine-rich repeat	636..661	CDD:275381	9/26 (35%)
AT2G17020	NP_565400.1	F-box	22..60	CDD:279040
		leucine-rich repeat	53..87	CDD:275381	6/23 (26%)
		leucine-rich repeat	89..111	CDD:275381	5/21 (24%)
		leucine-rich repeat	112..137	CDD:275381	8/35 (23%)
		leucine-rich repeat	138..168	CDD:275381	9/30 (30%)
		leucine-rich repeat	169..215	CDD:275381	13/53 (25%)
		leucine-rich repeat	236..260	CDD:275381	9/25 (36%)
		AMN1	<246..394	CDD:187754	35/148 (24%)
		leucine-rich repeat	261..292	CDD:275381	5/30 (17%)
		leucine-rich repeat	294..315	CDD:275381	5/21 (24%)
		leucine-rich repeat	328..353	CDD:275381	6/24 (25%)
		AMN1	337..497	CDD:187754	40/159 (25%)
		leucine-rich repeat	354..379	CDD:275381	5/24 (21%)
		leucine-rich repeat	380..404	CDD:275381	6/23 (26%)
		leucine-rich repeat	405..429	CDD:275381	8/23 (35%)
		leucine-rich repeat	430..455	CDD:275381	2/24 (8%)
		leucine-rich repeat	456..481	CDD:275381	8/24 (33%)
		leucine-rich repeat	482..509	CDD:275381	8/26 (31%)
		leucine-rich repeat	510..529	CDD:275381	118/481 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910