DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and Fbxl22

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_780415.1	Gene:	Fbxl22 / 74165	MGIID:	1921415	Length:	236	Species:	Mus musculus

Alignment Length:	198	Identity:	51/198 - (25%)
Similarity:	86/198 - (43%)	Gaps:	42/198 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 SLSLRCSSI----SDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVSLSLADCINIAD 444
            |||..||.:    .|..|..|| |..||.||:.....          |:|.:.|||:  |.:.:.
Mouse    25 SLSRTCSQLRDVFEDPTLWPLL-HFHSLAELKKDNFR----------LSPALRSLSI--CWHSSR 76

  Fly   445 EAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNIVHSLPHL 509
            ..|.::...|.|..:.|:.:.|.:                         |.|..::.:.:..|:|
Mouse    77 VQVCSIEDWLKSALQRSICSQHES-------------------------LVNDFLLQVCNRCPNL 116

  Fly   510 TVLSLSGCSKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITD 574
            |.::||||..:|||.:..:..:..:||.|.|..|.|:|:.:|..:|.....|:.|.:|.|.:::.
Mouse   117 TSVTLSGCGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTLHVDFCRNVSA 181

  Fly   575 IGV 577
            .|:
Mouse   182 AGL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	10/25 (40%)
		AMN1	383..600	CDD:187754	51/198 (26%)
		leucine-rich repeat	431..456	CDD:275381	6/24 (25%)
		leucine-rich repeat	457..482	CDD:275381	2/24 (8%)
		leucine-rich repeat	483..508	CDD:275381	2/24 (8%)
		leucine-rich repeat	509..534	CDD:275381	9/24 (38%)
		leucine-rich repeat	535..560	CDD:275381	9/24 (38%)
		leucine-rich repeat	561..585	CDD:275381	5/17 (29%)
		leucine-rich repeat	586..610	CDD:275381
		leucine-rich repeat	636..661	CDD:275381
Fbxl22	NP_780415.1	F-box-like	3..43	CDD:403981	6/17 (35%)
		LRR 1	15..40		5/14 (36%)
		LRR 2	43..72		12/41 (29%)
		AMN1	45..>200	CDD:187754	44/178 (25%)
		LRR 3	98..123		7/49 (14%)
		leucine-rich repeat	116..141	CDD:275381	9/24 (38%)
		LRR 4	124..149		8/24 (33%)
		leucine-rich repeat	142..167	CDD:275381	9/24 (38%)
		LRR 5	150..175		7/24 (29%)
		leucine-rich repeat	168..193	CDD:275381	5/17 (29%)
		LRR 6	176..201		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900