DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32085 and Fbxo39

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:XP_006533964.2 Gene:Fbxo39 / 628100 MGIID:3505735 Length:480 Species:Mus musculus


Alignment Length:474 Identity:96/474 - (20%)
Similarity:161/474 - (33%) Gaps:162/474 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   249 PHLHHPYGSMGINAASPLIMQHQLHPPPIH----SIEQLM-------LDDRFLSRFFQYFSPYER 302
            |||..|        .||  ..:.:|..|:.    .:.||.       |.|..|.|.|.:....:|
Mouse    19 PHLGKP--------CSP--HHYAVHQGPLMDEDCEVTQLQEQSCWATLPDVCLRRVFWWLGDRDR 73

  Fly   303 RILAQVCIKWRDTLYRSP--RY----WSGLLPTLQCREL-----------RQMPGCDRGKL--YN 348
            ...|.||.||...:|.:.  ||    :||....:...|.           |.:...:...|  ||
Mouse    74 SRAALVCRKWNQIMYSADLWRYRTITFSGRPSRVHASEFESALWYIKKFGRYLEHLEIKFLNPYN 138

  Fly   349 SLIRRGFHA-----LGLVGASDE--DALDVVH--------------------SFPL--ASKHVHS 384
            :::.:.|..     |..:|.|:.  .:|.:.|                    ||.|  ..||:..
Mouse   139 AVLTKKFQVTMRGLLSCLGKSNNRLRSLSIQHLELDRLVWRNSIRGSLIKSLSFFLKKMGKHLDH 203

  Fly   385 LSLRCSSIS-DRGLETL--LDHLQSLFELELAGCNEVTEAGLWACLTPRIVSLSLADCINIAD-- 444
            |||:.:.:: ::|...|  |.::|          ||                 ::|..:||.|  
Mouse   204 LSLKGARLTVEQGCHILNSLSYMQ----------NE-----------------NMASELNIEDFF 241

  Fly   445 ---EAVGAVAQLLPSLYEF------SLQAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIV 500
               .||...:|...::..|      :|....::|..|...|...:.:|..:.:: |     |   
Mouse   242 SHHLAVYGSSQFNKAMATFRNLTFLTLNYNCISDELLETLSENNAGTLRTMNIK-C-----H--- 297

  Fly   501 NIVHSLPHLTVLSLSGCSKLTDDG----VELIAENLQK-------------LRALDLSWC----- 543
              ||. ||..|:.....:||....    |....|.:.|             :|::.|..|     
Mouse   298 --VHD-PHGQVVWGMSWAKLARQASNLKVNFFFERVMKYERLARILLQEIPVRSISLRSCYFSDP 359

  Fly   544 -----PRITDA------SLEYIACDLNQLEELTLDRCVHITDIG---VGYISTMLSLTALFLRWC 594
                 |.:||.      :|:.:..:.|...| :||..:|:..:.   :.|......|...|:...
Mouse   360 DWSMRPTLTDLLPTFRNTLQKLTFEFNNNHE-SLDEQLHLLILACRKLFYFKIWAFLDVKFVERI 423

  Fly   595 SQVRDFGLQHLCSMRNLQV 613
            .:.::.|   .||:..|:|
Mouse   424 LKSQEEG---QCSLHTLKV 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 6/26 (23%)
AMN1 383..600 CDD:187754 49/266 (18%)
leucine-rich repeat 431..456 CDD:275381 7/29 (24%)
leucine-rich repeat 457..482 CDD:275381 5/30 (17%)
leucine-rich repeat 483..508 CDD:275381 5/24 (21%)
leucine-rich repeat 509..534 CDD:275381 5/28 (18%)
leucine-rich repeat 535..560 CDD:275381 7/40 (18%)
leucine-rich repeat 561..585 CDD:275381 5/26 (19%)
leucine-rich repeat 586..610 CDD:275381 5/23 (22%)
leucine-rich repeat 636..661 CDD:275381
Fbxo39XP_006533964.2 F-box-like 53..94 CDD:372399 12/40 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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