DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32085 and Lrrc29

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:XP_006255593.1 Gene:Lrrc29 / 502201 RGDID:1593150 Length:673 Species:Rattus norvegicus


Alignment Length:602 Identity:147/602 - (24%)
Similarity:222/602 - (36%) Gaps:165/602 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   154 QLQQSQQQHL--QLQASTLINSNHHVMVGPAPPT-----GMPLGAPPTPTVKSIAKQMNITIPGG 211
            |:.||...||  .||:         :.:|...||     .:.||.|       :.:.::::    
  Rat   135 QVLQSVAYHLGPHLQS---------LCLGGGSPTEASFLALILGCP-------VLRTLDLS---- 179

  Fly   212 GVNPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMGINAASPLIMQHQLHPPP 276
                |..:..|.|.:.||...|..      :||.|.        |...:|.|.       |..  
  Rat   180 ----GCNSLFTSGTLLAQPETAQC------VRKALS--------GLRDLNLAG-------LRD-- 217

  Fly   277 IHSIEQLMLDDRFLSRFFQYFSPYERRILA------QVCIKWRDTLYRSPRYWSGLLPT-LQCRE 334
                    |.|...:.....|...||..||      ::...|..|   ||:..|   |: |....
  Rat   218 --------LTDLSFNHLSSCFPSLERLSLAYCHLTFELGSTWGST---SPQASS---PSQLSFHN 268

  Fly   335 LRQMPGCDRGKLYNSLIRRGFHALGLVGA----SDEDALDVVHSFPLASKHVHSLSLRCSSISDR 395
            |.|......|.|         .||.|.|.    ....||..|....|...:::|    |..:|..
  Rat   269 LLQFIKERAGTL---------RALDLSGTGLPPEALQALGQVTGLKLEELNLNS----CKDLSSE 320

  Fly   396 GLETLLDHLQSLFELELAGCNEVTEAGLWA-----------------------CLT----PRIVS 433
            .:.||......|..|:|:||:|:|:..|.|                       |:.    ..:.|
  Rat   321 AVATLCRQQPGLTSLDLSGCSELTDRALLAVSRGLHHLRHLSLKKLQRLTDAGCIALGALHELQS 385

  Fly   434 LSLADCINIAD----EAVGAVAQLLPSLYEFSLQAY--HVTDAALGYFSPKQSHSLSILRLQSCW 492
            |.:|:|..::.    :.:|:|.:..|:|....| ||  .:.||::....|....||.:|.|.||.
  Rat   386 LDMAECCLVSGRELAQVLGSVRRAPPALTSLRL-AYCSSLKDASVLSMIPALGPSLKVLDLSSCV 449

  Fly   493 ELTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVELIAE--------------------------- 530
            .|||..:..|...|.||:||.|:.|.:|.|.|:..:.|                           
  Rat   450 ALTNQTMQAICTYLIHLSVLRLAWCKELQDWGLLGLKEPSDEPVLNPQLHQEVENQAPDHQEPSS 514

  Fly   531 --------NLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIG-VGYISTMLSL 586
                    .||.|:.|||:.|.::|||||..: ....||.:|:|......||:| |.......||
  Rat   515 EPQGSSLLMLQALQELDLTACSKLTDASLAKV-LQFPQLRQLSLSLLPAFTDMGLVAVARGCPSL 578

  Fly   587 TALFLRWCSQVRDFG-LQHLCSMRNLQVLSLAGCPLLTSSGLSSLIQ-LRHLQELELTNCPGASH 649
            ..|.|..||.:.|.| :|.......||.|:|:.|..:|...|.::.| .:.|:.|::..|||.:.
  Rat   579 ERLTLSHCSHLSDEGWVQAARLWPRLQHLNLSSCSQVTEQTLDTIGQACKQLRVLDVAMCPGINM 643

  Fly   650 ELFDYLKEHLPRCLIIE 666
            ....:.:..||:...|:
  Rat   644 AAVKHFQAQLPQVTCIQ 660

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 5/23 (22%)
AMN1 383..600 CDD:187754 76/285 (27%)
leucine-rich repeat 431..456 CDD:275381 6/28 (21%)
leucine-rich repeat 457..482 CDD:275381 7/26 (27%)
leucine-rich repeat 483..508 CDD:275381 10/24 (42%)
leucine-rich repeat 509..534 CDD:275381 10/59 (17%)
leucine-rich repeat 535..560 CDD:275381 10/24 (42%)
leucine-rich repeat 561..585 CDD:275381 7/24 (29%)
leucine-rich repeat 586..610 CDD:275381 8/24 (33%)
leucine-rich repeat 636..661 CDD:275381 6/24 (25%)
Lrrc29XP_006255593.1 leucine-rich repeat 124..142 CDD:275381 3/6 (50%)
LRR_RI <170..410 CDD:238064 61/304 (20%)
leucine-rich repeat 173..206 CDD:275381 9/54 (17%)
leucine-rich repeat 207..232 CDD:275381 6/41 (15%)
leucine-rich repeat 233..279 CDD:275381 13/51 (25%)
leucine-rich repeat 280..300 CDD:275381 7/28 (25%)
AMN1 292..480 CDD:187754 51/192 (27%)
leucine-rich repeat 306..331 CDD:275381 6/28 (21%)
leucine-rich repeat 332..357 CDD:275381 9/24 (38%)
leucine-rich repeat 358..439 CDD:275381 15/81 (19%)
leucine-rich repeat 383..408 CDD:275381 6/24 (25%)
leucine-rich repeat 413..437 CDD:275381 7/24 (29%)
leucine-rich repeat 440..465 CDD:275381 10/24 (42%)
leucine-rich repeat 466..526 CDD:275381 10/59 (17%)
leucine-rich repeat 527..577 CDD:275381 18/50 (36%)
AMN1 <564..>638 CDD:187754 23/73 (32%)
leucine-rich repeat 578..603 CDD:275381 8/24 (33%)
leucine-rich repeat 604..629 CDD:275381 8/24 (33%)
leucine-rich repeat 630..655 CDD:275381 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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