DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and gadr-5

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001252264.2	Gene:	gadr-5 / 4927064	WormBaseID:	WBGene00045058	Length:	915	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	44/211 - (20%)
Similarity:	86/211 - (40%)	Gaps:	57/211 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   445 EAVGAVAQLL-PSLYEFSLQAYHVTDA--------ALGYFSPKQSHSLSILRLQSCWELTNHGIV 500
            ||:.:...|| |..|:|..:|..:.::        |..|:    :.::.|:.          .:.
Worm   260 EAIFSKLLLLNPKAYKFIAKATQIQESVVIGKRVHAQHYY----ARNIDIMT----------SLT 310

  Fly   501 NIVH--SLPHLTVLSLSGC-SKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLE 562
            ::::  ||..:..|.:..| |:||...|.||...|..|::||:|..| ::......:......|:
Worm   311 SVLYGKSLAKIHSLDIGECRSQLTPGWVRLIGTMLPSLQSLDISNKP-LSKEDFSQLCNFFQNLQ 374

  Fly   563 ELTL-DRCVHITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSG 626
            :|.: |.||.                             .||.:..::||:|||:......|::.
Worm   375 KLNISDTCVK-----------------------------KLQGISKLKNLKVLSMRNLQFRTATD 410

  Fly   627 LSSLIQLRHLQELELT 642
            :..|.:|:.|..|:::
Worm   411 MLDLFKLKGLVALDVS 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	32/167 (19%)
		leucine-rich repeat	431..456	CDD:275381	4/11 (36%)
		leucine-rich repeat	457..482	CDD:275381	5/32 (16%)
		leucine-rich repeat	483..508	CDD:275381	3/26 (12%)
		leucine-rich repeat	509..534	CDD:275381	9/25 (36%)
		leucine-rich repeat	535..560	CDD:275381	5/24 (21%)
		leucine-rich repeat	561..585	CDD:275381	5/24 (21%)
		leucine-rich repeat	586..610	CDD:275381	2/23 (9%)
		leucine-rich repeat	636..661	CDD:275381	2/7 (29%)
gadr-5	NP_001252264.2	MFS	<15..201	CDD:119392
		LRR	<311..514	CDD:227223	33/146 (23%)
		leucine-rich repeat	348..372	CDD:275382	5/24 (21%)
		LRR_4	371..>402	CDD:289563	12/59 (20%)
		leucine-rich repeat	373..396	CDD:275382	8/51 (16%)
		leucine-rich repeat	397..419	CDD:275380	6/21 (29%)
		leucine-rich repeat	420..449	CDD:275380	2/7 (29%)
		leucine-rich repeat	450..473	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162700
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930