Protein Alignment CG32085 and Skp2

DIOPT Version :10

• Sequence 1: NP_729732.1
• Gene: CG32085 / 39311
• FlyBaseID: FBgn0052085
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 131/587 - (22%)
• Similarity: 218/587 - (37%)
• Gaps: 138/587 - (23%)

  Fly    55 PAAPSGKT-SVMERVTNALCGGGNSNSNSGSN-----SSNSNTSSASATAATSPASNANPPQTPD 113
            |::||..| ..:|.:...:.....|:|::.|.     |:.|:.:|...|...|.:..|:..|...
  Fly    47 PSSPSALTFEALEEMGIGMLDSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQ 111

  Fly   114 KPSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQHMQ-LQQSQQQHLQLQASTLINSNHHV 177
            :.|.||:   |.||:  ....|::|    |...:|..:.:| |.|:::..|..:.|.  |||
  Fly   112 RLSLGST---GDITL--DSPAVEDS----LSMSRQSAEKLQILAQAKRSSLGSEGSG--NSN--- 162

  Fly   178 MVGPAPPTGMPLGAPPTPTVKSIAKQMNITIPGGGVNPGSPTFSTMGMVAAQKAAAS-------- 234
              .|:.....||.          |...|..|.|.......|:.|.:..|...|..::
  Fly   163 --SPSKRLRNPLA----------AVTCNNQIDGTASLNFQPSTSRLAQVRQAKKPSTTNITTRIV 215

  Fly   235 AGGTPLQLRKQLPNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQLMLDDRFLSRFFQYFSP 299
            |..:....|....:.|:     :.|||...                   .|.|..|...|::...
  Fly   216 AADSFFVFRTPAMSAHI-----NSGINYFE-------------------RLSDEILLDIFKWLPK 256

  Fly   300 YERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGKLYNSLIRRGFHALGLVGAS 364
            .....:|.||.:: :...|....|:.|  .|..|.:|  ||.     ...::|||...:.|...|
  Fly   257 KTLLRMATVCRRF-NRCSRDETLWTRL--DLGLRTIR--PGA-----LEQIVRRGVLVIRLAQTS 311

  Fly   365 DEDALDVVHSFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAG-------C-----NE 417
            .::.....::....:: :..|.|..:||:...|.|||.|.:.|.::.|..       |     ||
  Fly   312 IQEPAFAPYTEVFRTR-LQYLDLSMASITRSSLLTLLSHCRQLKKISLENIELDDDICAEIAKNE 375

  Fly   418 VTEAGLWACLTPRIVSLSLADCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQSHS 482
            ..||          |:|::|.  .:...:|..:.:.|.||                       .|
  Fly   376 ALEA----------VNLTMAS--GLTSNSVRLMMESLTSL-----------------------SS 405

  Fly   483 LSILRLQSCWELTNHGIVNIV-HSLPHLTVLSLSGCSK-LTDDGVELIAENLQKLRALDLSWCPR 545
            |:|    |..:|:...:..:| |..|:|..|:::||.: |.|..|..:.:...:|..||||.|..
  Fly   406 LNI----SWTDLSADAVTALVTHISPNLIRLNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNS 466

  Fly   546 ITDASLEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRN 610
            :|...:..| .....||.|::.||..|.......:.:|.|||.|.:        ||:....:|..
  Fly   467 LTPTVITAI-MKFKMLEYLSVSRCYLIPATKFIELKSMPSLTYLDI--------FGMLSDTAMEV 522

  Fly   611 LQ 612
            |:
  Fly   523 LE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	F-box_FBXL16	283..325	CDD:438899	9/41 (22%)
		leucine-rich repeat	382..406	CDD:275381	9/23 (39%)
		AMN1	383..600	CDD:187754	57/230 (25%)
		leucine-rich repeat	431..456	CDD:275381	5/24 (21%)
		leucine-rich repeat	457..482	CDD:275381	1/24 (4%)
		leucine-rich repeat	483..508	CDD:275381	6/25 (24%)
		leucine-rich repeat	509..534	CDD:275381	7/25 (28%)
		leucine-rich repeat	535..560	CDD:275381	8/24 (33%)
		leucine-rich repeat	561..585	CDD:275381	7/23 (30%)
		leucine-rich repeat	586..610	CDD:275381	6/23 (26%)
		leucine-rich repeat	636..661	CDD:275381
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	9/61 (15%)
		leucine-rich repeat	302..327	CDD:275381	2/24 (8%)
		AMN1	309..480	CDD:187754	47/211 (22%)
		leucine-rich repeat	328..352	CDD:275381	9/23 (39%)
		leucine-rich repeat	353..376	CDD:275381	4/22 (18%)
		leucine-rich repeat	377..402	CDD:275381	7/36 (19%)
		leucine-rich repeat	403..428	CDD:275381	8/51 (16%)
		leucine-rich repeat	429..455	CDD:275381	7/25 (28%)
		leucine-rich repeat	456..480	CDD:275381	8/24 (33%)
		leucine-rich repeat	481..500	CDD:275381	6/18 (33%)
		leucine-rich repeat	506..529	CDD:275381	7/27 (26%)