DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and Fbxl7

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001102015.1 Gene:Fbxl7 / 361907 RGDID:1305813 Length:491 Species:Rattus norvegicus


Alignment Length:639 Identity:137/639 - (21%)
Similarity:226/639 - (35%) Gaps:206/639 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 GGNS-----NSNSGSNSSNSNTSSASATAATSPASNANPPQTPDKPSRG-SSPSPGGI---TMPG 130
            |.|:     :...||:|.:|:.||::....|....|....:..|...|. |:|||..|   .:||
  Rat     2 GANNGKQYGSEGKGSSSVSSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPALPG 66

  Fly   131 GQSQVQNSTHHLLQQQQQQQQHMQLQQSQQQHLQLQASTLINSNHHVMVGPAPPTGMPLGAPPTP 195
            .|:...:||                           :|:.|......||...|||          
  Rat    67 FQNGRGSST---------------------------SSSSITGETVAMVHSPPPT---------- 94

  Fly   196 TVKSIAKQMNITIPGGGVNPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMGI 260
                                                                  .|.||...:  
  Rat    95 ------------------------------------------------------RLTHPLIRL-- 103

  Fly   261 NAASPLIMQHQLHPPPIHSIEQLMLDDRFLSRFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSG 325
             |:.|...|..:...|.||:.|:          |.:....:....|:||.:|.:..: .||.|  
  Rat   104 -ASRPQKEQASIDRLPDHSMVQI----------FSFLPTNQLCRCARVCRRWYNLAW-DPRLW-- 154

  Fly   326 LLPTLQCRELRQMPGCDRGKLYNSLIRRGFHALGLVGASDEDALDVVHSFPLASKHVHSLSLRCS 390
                   |.:|                       |.|    :.::|..:..:.::.:      |.
  Rat   155 -------RTIR-----------------------LTG----ETINVDRALKVLTRRL------CQ 179

  Fly   391 SISD--RGLETLLDHLQSLFELELAGCNEVTEAGLW--ACLTPRIVSLSLADCINIADEAVGAVA 451
            ...:  ..|||::          ::||..:|:.||:  |...|.:..|.::.|.||::|||..|.
  Rat   180 DTPNVCLMLETVI----------VSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVV 234

  Fly   452 QLLPSLYEFSLQ------AYHVTDAALGYFSPKQSHSLSI--LRLQSCWELTNHGIVNIVHSLPH 508
            .|.|:|....:.      ...:|..|....||.....:||  |.:..|:.|.:.|:..|......
  Rat   235 SLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQ 299

  Fly   509 LTVLSLSGCSKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHIT 573
            ||.|.|..|.:|||:|:..:......::.|.:|.|..::|..|..||...::|..|::..|..||
  Rat   300 LTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRIT 364

  Fly   574 DIGVGYISTMLS-LTALFLRWCSQVRDFGLQHLC-SMRNLQVLSLAGCPLLTSSGLSSL-IQLRH 635
            |:|:.|::...| |..|..|.|..:.|.|:::|. :...|:.|.:..|||::.:||.|| :...:
  Rat   365 DVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFN 429

  Fly   636 LQELELTNCPG-------------------------ASHELFDYLKEHLPRCLI 664
            |:.|.|.:|..                         .|.|...::|.|..||:|
  Rat   430 LKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVI 483

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 4/25 (16%)
AMN1 383..600 CDD:187754 62/229 (27%)
leucine-rich repeat 431..456 CDD:275381 9/24 (38%)
leucine-rich repeat 457..482 CDD:275381 5/30 (17%)
leucine-rich repeat 483..508 CDD:275381 7/26 (27%)
leucine-rich repeat 509..534 CDD:275381 9/24 (38%)
leucine-rich repeat 535..560 CDD:275381 7/24 (29%)
leucine-rich repeat 561..585 CDD:275381 8/23 (35%)
leucine-rich repeat 586..610 CDD:275381 7/24 (29%)
leucine-rich repeat 636..661 CDD:275381 8/49 (16%)
Fbxl7NP_001102015.1 F-box-like 114..160 CDD:289689 14/88 (16%)
leucine-rich repeat 129..151 CDD:275381 4/22 (18%)
leucine-rich repeat 154..187 CDD:275381 7/74 (9%)
AMN1 <185..366 CDD:187754 53/190 (28%)
leucine-rich repeat 188..213 CDD:275381 9/34 (26%)
leucine-rich repeat 214..234 CDD:275381 7/19 (37%)
leucine-rich repeat 240..273 CDD:275381 5/32 (16%)
leucine-rich repeat 274..299 CDD:275381 6/24 (25%)
AMN1 297..464 CDD:187754 45/166 (27%)
leucine-rich repeat 300..325 CDD:275381 9/24 (38%)
leucine-rich repeat 326..351 CDD:275381 7/24 (29%)
leucine-rich repeat 352..377 CDD:275381 8/24 (33%)
leucine-rich repeat 378..403 CDD:275381 7/24 (29%)
leucine-rich repeat 404..429 CDD:275381 9/24 (38%)
leucine-rich repeat 430..453 CDD:275381 4/22 (18%)
leucine-rich repeat 456..480 CDD:275381 4/23 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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