DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and Kdm2a

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:XP_038939767.1 Gene:Kdm2a / 361700 RGDID:1309419 Length:1166 Species:Rattus norvegicus


Alignment Length:582 Identity:119/582 - (20%)
Similarity:195/582 - (33%) Gaps:188/582 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 CGGGNSNSNSGSNSSNSNTSSASATAATSPASNANPPQTPDKPSRGS------SP-SPGGI---T 127
            |...:|:..:.......:...|.......|..:...|.||...|..|      .| ||.|:   :
  Rat   680 CYQEDSSEKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRS 744

  Fly   128 MPGGQSQVQNSTHHLLQQQQQQQQHMQLQQSQQQHLQLQAS--TLINSNHHVMVGPAPPTGMPLG 190
            .||...    |.||...:.::.:        ::|.|:|||:  |::....:      .|:|.   
  Rat   745 SPGAGP----SDHHSASRDERFK--------RRQLLRLQATERTMVREKEN------NPSGK--- 788

  Fly   191 APPTPTVKSIAKQMNITIPGG--GVNPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHH 253
                   |.:::.....|.|.  .|....||....|.....|..|....: ..||   |||.   
  Rat   789 -------KELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASS-ANLR---PNPR--- 839

  Fly   254 PYGSMGINAASPLIMQHQLHPPPIHSIEQLM---------------------------------L 285
                        ::|||.....|....|:.:                                 .
  Rat   840 ------------VLMQHCPARNPQRGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDG 892

  Fly   286 DDRFLSR-----FFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGK 345
            |:.::.|     .|:|.|..|.....:||..|    |:    |        |        ||: :
  Rat   893 DESWMQREVWMSVFRYLSRRELCECMRVCKTW----YK----W--------C--------CDK-R 932

  Fly   346 LYNSLIRRGFHALGLVGASDEDALD-VVHSFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFE 409
            |:..:      .|....|....||. ::...|:      ||.|..::||.:.|..|::.|..|.:
  Rat   933 LWTKI------DLSRCKAIVPQALSGIIKRQPV------SLDLSWTNISKKQLTWLVNRLPGLKD 985

  Fly   410 LELAGCNEVTEAGLWACLTPRIVSLSLADCINIADEAVGAV------------AQLLPSLYEFSL 462
            |.||||:....:.|.....|.:.:|.|...:.|.|..:..:            ...|.::.:|.|
  Rat   986 LLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRL 1050

  Fly   463 QAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVEL 527
            ....:|||.              |||             |:..:|.|:.|.||.||.|||....|
  Rat  1051 AGLDITDAT--------------LRL-------------IIRHMPLLSRLDLSHCSHLTDQSSNL 1088

  Fly   528 I----AENLQKLRALDLSWCPRITDASLEYI-------ACDLNQLEELTLDRCVH-ITDIGV 577
            :    :.....|..|:::.|.::||.:|.::       ..||...:::|...|.| |:|:.:
  Rat  1089 LTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSI 1150

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 8/23 (35%)
AMN1 383..600 CDD:187754 54/219 (25%)
leucine-rich repeat 431..456 CDD:275381 5/36 (14%)
leucine-rich repeat 457..482 CDD:275381 5/24 (21%)
leucine-rich repeat 483..508 CDD:275381 4/24 (17%)
leucine-rich repeat 509..534 CDD:275381 10/28 (36%)
leucine-rich repeat 535..560 CDD:275381 8/31 (26%)
leucine-rich repeat 561..585 CDD:275381 5/18 (28%)
leucine-rich repeat 586..610 CDD:275381
leucine-rich repeat 636..661 CDD:275381
Kdm2aXP_038939767.1 cupin_RmlC-like 204..304 CDD:424065
JHD 309..>344 CDD:407680
CTD_KDM2A 455..522 CDD:412025
zf-CXXC <581..614 CDD:366873
PHD_KDM2A 624..680 CDD:277113 119/582 (20%)
F-box-like 900..938 CDD:403981 13/68 (19%)
leucine-rich repeat 934..958 CDD:275381 4/29 (14%)
AMN1 936..1142 CDD:187754 55/244 (23%)
leucine-rich repeat 959..982 CDD:275381 8/28 (29%)
leucine-rich repeat 983..1006 CDD:275381 7/22 (32%)
leucine-rich repeat 1007..1044 CDD:275381 5/36 (14%)
leucine-rich repeat 1045..1069 CDD:275381 9/50 (18%)
leucine-rich repeat 1070..1099 CDD:275381 10/28 (36%)
leucine-rich repeat 1100..1124 CDD:275381 6/23 (26%)
leucine-rich repeat 1125..1144 CDD:275381 4/18 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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