DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32085 and CG15056

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	96/398 - (24%)
Similarity:	154/398 - (38%)	Gaps:	121/398 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 FHALGLVGASDEDALDVVHSFPLASK-------------HVHSLSLRCSSISDRGLETLLDH--L 404
            |.:..::...|...|||:....|.|:             :|.|..||.|.:.:  ||.:::.  |
  Fly     3 FISFSVISRFDFFWLDVLKQLDLKSRISFAASCDMFENIYVRSSPLRLSRVVN--LEEMIEFSLL 65

  Fly   405 QSLFELELAGCN-EVTEAGLWACLTP---------RIVSLSLADCINIADEAVGAVAQLLPSLYE 459
            ::...:||:|.: |:...|..   ||         |::|:.|.....||.|.
  Fly    66 ETKLFVELSGSDIEIIRGGPH---TPMFSHFEDFIRLMSIRLTKVNEIALEG------------- 114

  Fly   460 FSLQAYHVTDAALGYFSPKQSHS-LSILRLQSC---------WELTNH-------------GIVN 501
            |.|..|...:|      |:.|.| |:.:.|:.|         ||...|             |  :
  Fly   115 FQLTQYKWFNA------PETSFSNLTYVSLRRCQLNDENLVGWEFLTHLETLDLRYNDRLTG--S 171

  Fly   502 IVHSLP-HLTVLSLSGCSKLTDDGVELIAEN----LQKLRALDL----SW---------CP---- 544
            .:.||| .|..|.::||..|..:  :||..|    |::|||.||    .|         ||
  Fly   172 CLMSLPTSLLSLYITGCRNLCPN--QLIFLNRIPRLRELRASDLMPGGHWHIYRDLVLACPLLVM 234

  Fly   545 -RITDASL---EYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTAL---FLR---WCSQVRD 599
             .|:..||   ||...:|..|:.|.:.  .|.||.....:|..:.::.|   |||   :......
  Fly   235 VEISICSLNRDEYRLGELRYLQSLVIK--AHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSG 297

  Fly   600 F----GLQHLCSMRNLQVLSLAGCPLLTSSGLSSLIQLRH---LQELELTNCPGASHELFDYLKE 657
            |    .|..:...|.|:||.:...|...    :.|::||:   |:.|:|:|.|..::|:...|..
  Fly   298 FVSANALSIISRFRQLRVLKMPNQPYRP----NDLLRLRNLTFLETLDLSNSPYITNEVVIELVI 358

  Fly   658 HLPRCLII 665
            .:|...::
  Fly   359 GIPNLSVL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	8/25 (32%)
		AMN1	383..600	CDD:187754	70/283 (25%)
		leucine-rich repeat	431..456	CDD:275381	5/24 (21%)
		leucine-rich repeat	457..482	CDD:275381	6/24 (25%)
		leucine-rich repeat	483..508	CDD:275381	10/47 (21%)
		leucine-rich repeat	509..534	CDD:275381	9/28 (32%)
		leucine-rich repeat	535..560	CDD:275381	14/45 (31%)
		leucine-rich repeat	561..585	CDD:275381	6/23 (26%)
		leucine-rich repeat	586..610	CDD:275381	6/33 (18%)
		leucine-rich repeat	636..661	CDD:275381	7/24 (29%)
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	5/22 (23%)
		leucine-rich repeat	157..179	CDD:275381	4/23 (17%)
		leucine-rich repeat	180..204	CDD:275381	8/25 (32%)
		leucine-rich repeat	205..231	CDD:275381	8/25 (32%)
		leucine-rich repeat	232..285	CDD:275381	13/54 (24%)
		leucine-rich repeat	286..326	CDD:275381	9/43 (21%)
		AMN1	306..>376	CDD:187754	16/65 (25%)
		leucine-rich repeat	337..362	CDD:275381	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840