DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and fbxl6

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001296447.1 Gene:fbxl6 / 323163 ZFINID:ZDB-GENE-060810-162 Length:564 Species:Danio rerio


Alignment Length:671 Identity:122/671 - (18%)
Similarity:227/671 - (33%) Gaps:224/671 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 NTSSASATAATSPASNANPPQTPDKPSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQHMQ 154
            :|.:.:::|..|.|.::....:|.||::..:|             ::.....|...:.::::...
Zfish     3 STVAQASSAEMSAAQSSRAETSPTKPAKRKAP-------------LKRKADSLKDDKSKKKKRKP 54

  Fly   155 LQQSQQQHLQLQASTLINSNHHVMVGPAPPTGMPLGAPPTPTVKSIAKQMNITIPGGGVNPGSPT 219
            ::::            :..|:.|..|                     :.|.:.|  ..::.|...
Zfish    55 VKRT------------VRPNYTVQEG---------------------EDMLLII--SNISSGDSV 84

  Fly   220 FSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMGINAASPL---IMQHQLHPPPIHSIE 281
            :.....|..:|.......|.                ||......:|:   :::.:......|.:.
Zfish    85 WKPKRKVGKKKKTNKKAKTK----------------GSTSKKEKAPVKTEVLKVREETDDKHDVM 133

  Fly   282 QLMLDDRF-----------LSRFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPT-LQCRE 334
            .....|||           |.:.|| |:.::...:..:|     .:.|..|.|:|...: :..|.
Zfish   134 DSAKTDRFDHWGQSLPLEILVKIFQ-FAVFQDGAVPLLC-----RVGRVCRLWNGAASSPILWRS 192

  Fly   335 L-----------RQMPGCDRGKLYNSLIRRGFHALGLVGASDEDALDVVHSFPLA--SKHVHSLS 386
            :           .|:||.:: |:.|:           |....|:.|..:..|.|.  .|:|    
Zfish   193 VSIGYCWIEPGKSQLPGTEQ-KIKNT-----------VDWLAENRLFQLREFSLCHWKKNV---- 241

  Fly   387 LRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVSLSLADCINIADEAVGAVA 451
                   |..::.:.....||..|:|:.|..:||..        ..:|. |||.::.|..|....
Zfish   242 -------DYVIQKVSQSCLSLHSLKLSYCTGMTEKA--------FQNLG-ADCQSLEDINVQHSE 290

  Fly   452 QLLPSLYEFSLQAY----------HVT--DAALGYFSPKQSHSLSILRLQS-------------- 490
            ..:..|..| |:||          |.|  |..|...|......|.:|.:.:              
Zfish   291 INVDGLVSF-LEAYGNQIKKIYFTHSTKSDKLLSALSKGCCPELRLLEINTKLDGGYSQLPICIQ 354

  Fly   491 -----CWELTNHGIVNI------VHSLPHLT---------VLSLSGCSKLTDDGVELIAENLQKL 535
                 |.:|....::|:      :.::|..|         .::.|..|.:||:.:..:......|
Zfish   355 GLQIGCPKLQTFRLMNVTAVPKMIRNIPSSTCGFPMLEELCIATSFHSFMTDNDLNNVLHGSPNL 419

  Fly   536 RALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYIS-TMLS----LTALFLRWCS 595
            |.|||....|||...|..:.|:  :||      |.:   .|:.:.| ||::    :..|..:|.:
Zfish   420 RVLDLRGGSRITPTGLYALPCE--RLE------CFY---WGLYFNSNTMVASKKGIHMLAQKWSN 473

  Fly   596 QVRDFG-----------------LQHLCSMRNLQVLSLAGCPLLTSSGLSSLI-QLRHLQELELT 642
            .:|:..                 |.|...:...:.|:|:|.. :|||.|..|| |...|:.|.|:
Zfish   474 TLRELDLANQPFSEEDLEIAMGHLAHSVGVEFFRSLNLSGTK-ITSSALRLLINQAPALKYLNLS 537

  Fly   643 NCPGASHELFDYLKEHLPRCL 663
            :|            .:|||.|
Zfish   538 SC------------RYLPRGL 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 2/23 (9%)
AMN1 383..600 CDD:187754 55/267 (21%)
leucine-rich repeat 431..456 CDD:275381 6/24 (25%)
leucine-rich repeat 457..482 CDD:275381 10/36 (28%)
leucine-rich repeat 483..508 CDD:275381 5/49 (10%)
leucine-rich repeat 509..534 CDD:275381 5/33 (15%)
leucine-rich repeat 535..560 CDD:275381 10/24 (42%)
leucine-rich repeat 561..585 CDD:275381 7/24 (29%)
leucine-rich repeat 586..610 CDD:275381 5/40 (13%)
leucine-rich repeat 636..661 CDD:275381 5/24 (21%)
fbxl6NP_001296447.1 F-box-like 147..195 CDD:289689 10/53 (19%)
AMN1 213..396 CDD:187754 40/214 (19%)
leucine-rich repeat 229..254 CDD:275381 5/35 (14%)
leucine-rich repeat 255..280 CDD:275381 10/33 (30%)
leucine-rich repeat 281..306 CDD:275381 7/25 (28%)
leucine-rich repeat 307..334 CDD:275381 5/26 (19%)
leucine-rich repeat 335..362 CDD:275381 2/26 (8%)
AMN1 <391..>542 CDD:187754 40/174 (23%)
leucine-rich repeat 391..418 CDD:275381 4/26 (15%)
leucine-rich repeat 419..438 CDD:275381 9/18 (50%)
leucine-rich repeat 445..473 CDD:275381 7/30 (23%)
leucine-rich repeat 475..505 CDD:275381 3/29 (10%)
leucine-rich repeat 506..530 CDD:275381 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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