DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and Fbxl4

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001382505.1 Gene:Fbxl4 / 313101 RGDID:1305724 Length:621 Species:Rattus norvegicus


Alignment Length:567 Identity:132/567 - (23%)
Similarity:209/567 - (36%) Gaps:155/567 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 SNHHVMVGPAPPTGMPLGAPPTPTVKSIA---------KQMNITI----------PGGGVNPGSP 218
            |:|..:|..:..:  ||.|......|.:.         ..|:.|:          |..|....:.
  Rat    33 SSHRTIVSNSRTS--PLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTA 95

  Fly   219 TFSTMGMVAAQKAAASAGGTPLQLRKQLPNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQL 283
            .|.|.|....|..:||     |..|: .|:......|        ..|..:.|::|..:|.:|  
  Rat    96 VFRTYGTWWDQCPSAS-----LPFRR-TPSSFQSQDY--------VELTFEQQVYPTAVHVLE-- 144

  Fly   284 MLDDRFLSRFFQYFSPYERRILAQVC------------IKWRDTLYRSPRYWSGLLPTLQCRELR 336
                       .|......||||  |            ::| :||      ||.....:...:.|
  Rat   145 -----------TYHPGAVIRILA--CSANPYSPNPPAEVRW-ETL------WSERPTKVNASQAR 189

  Fly   337 QM-PGCDRGKLYNSLIRRGFHALGLVGASDEDALDVVHSFPLASKHVHSLSLRCSSISDRGLE-- 398
            |. |...:.....:|||...::..|...::.||: |:|    .:|....|||:.:.:....||  
  Rat   190 QFKPRIKQINFPTNLIRLEVNSSLLDYYTELDAV-VLH----GTKDKPLLSLKTALVDMNDLEDD 249

  Fly   399 -------TLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVS-----LSLADCINIADEAVGAVA 451
                   ..:|.|...|.....|  :....|.:..|...::.     |||.|...:|.     ..
  Rat   250 DYEEKDGCEMDALNKKFSSATLG--DGPSNGYFDKLPYELIQLILNHLSLPDLCRLAQ-----TC 307

  Fly   452 QLL------PSLY-EFSLQAY--HVTDAALGYFSPK----QSHSLS------------------- 484
            :||      |..| ..:||.|  .:.|.:|.:...:    |..:||                   
  Rat   308 RLLHQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQARCALVQWLNLSWTGNRGFISVSGFSRFLKV 372

  Fly   485 ----ILRLQ-SCWELTNHGIVNIVHSL-PHLTVLSLSGCSKLTDDGVELIAENLQKLRALD--LS 541
                ::||: ||....|...:.::..: |:|..|:||.|.||.......||    |||:|.  :.
  Rat   373 CGSELVRLELSCSHFLNDACLEVISEMCPNLQDLNLSSCDKLPPQAFGHIA----KLRSLKRLIL 433

  Fly   542 WCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYISTML-----SLTALFLRWCSQVRDFG 601
            :..::...:|..|.....:|:.|:|..||.|.|..|  |::|:     ||..|.|..|..:.:.|
  Rat   434 YRTKVEQTALLSILNFCAELQHLSLGSCVMIEDYDV--IASMIGAKCKSLRTLDLWRCKNITENG 496

  Fly   602 LQHL---CSMRNLQVLSLAGCPLLTSS-GLSSLI--QLRHLQELELT 642
            :..|   |::  |:.|.|..||.|.|| |..:.:  ||.:||:|.||
  Rat   497 IAELASGCAL--LEELDLGWCPTLQSSTGCFARLARQLPNLQKLFLT 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 7/32 (22%)
AMN1 383..600 CDD:187754 64/275 (23%)
leucine-rich repeat 431..456 CDD:275381 7/35 (20%)
leucine-rich repeat 457..482 CDD:275381 7/31 (23%)
leucine-rich repeat 483..508 CDD:275381 7/49 (14%)
leucine-rich repeat 509..534 CDD:275381 9/24 (38%)
leucine-rich repeat 535..560 CDD:275381 5/26 (19%)
leucine-rich repeat 561..585 CDD:275381 10/28 (36%)
leucine-rich repeat 586..610 CDD:275381 7/26 (27%)
leucine-rich repeat 636..661 CDD:275381 5/7 (71%)
Fbxl4NP_001382505.1 F-box-like 280..318 CDD:403981 8/42 (19%)
leucine-rich repeat 295..317 CDD:275381 7/26 (27%)
leucine-rich repeat 318..340 CDD:275381 6/21 (29%)
leucine-rich repeat 347..376 CDD:275381 3/28 (11%)
leucine-rich repeat 377..402 CDD:275381 5/24 (21%)
AMN1 394..601 CDD:187754 50/156 (32%)
leucine-rich repeat 403..427 CDD:275381 11/27 (41%)
leucine-rich repeat 428..452 CDD:275381 3/23 (13%)
leucine-rich repeat 453..480 CDD:275381 10/28 (36%)
leucine-rich repeat 481..506 CDD:275381 7/24 (29%)
leucine-rich repeat 507..534 CDD:275381 11/26 (42%)
leucine-rich repeat 535..560 CDD:275381 5/7 (71%)
leucine-rich repeat 561..586 CDD:275381
leucine-rich repeat 587..612 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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