DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and Amn1

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001008334.2	Gene:	Amn1 / 302032	RGDID:	1308119	Length:	258	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	72/266 - (27%)
Similarity:	113/266 - (42%)	Gaps:	78/266 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   426 CLTPRIVSLS--LADC----INIADEAVGAVAQ------------LLPSLYEFSLQAYHVTDAAL 472
            ||...|:::|  ::|.    .||.|..:..::.            |.|.:....|::.:::|.||
  Rat    14 CLRCLIINISRYISDIKYLPPNIKDRLIKIMSMRGRITDSNINEVLHPEVQRLDLRSCNISDVAL 78

  Fly   473 GYFSPKQSHSLSILRLQSCWE----LTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQ 533
            .:..  :...|..|.|:||.|    :|:.||..:..|...|..:||.||..:||:||..:|.|.|
  Rat    79 QHLC--KCRKLKALNLKSCREHRNSITSEGIKAVASSCSDLHEISLKGCCSVTDEGVLALALNCQ 141

  Fly   534 KLRALDLSWCPRITDASLE-------YIAC-DLN-------------------QLEELTLDRCVH 571
            .|:.:||..|..|||.||.       ::.| |.:                   ||||:.:..|::
  Rat   142 LLKIIDLGGCLSITDESLHALGKNCPFLQCVDFSTTQVSDNGVVALVSGPCAKQLEEINMGYCIN 206

  Fly   572 ITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSG---LSSLIQL 633
            :||..|     ..:|||     |.|:        |      :|...||||:|...   |..||..
  Rat   207 LTDKAV-----EAALTA-----CPQI--------C------ILLFHGCPLITDHSREVLEQLIGS 247

  Fly   634 RHLQEL 639
            |.|:::
  Rat   248 RKLKQV 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	60/222 (27%)
		leucine-rich repeat	431..456	CDD:275381	7/42 (17%)
		leucine-rich repeat	457..482	CDD:275381	4/24 (17%)
		leucine-rich repeat	483..508	CDD:275381	10/28 (36%)
		leucine-rich repeat	509..534	CDD:275381	11/24 (46%)
		leucine-rich repeat	535..560	CDD:275381	11/51 (22%)
		leucine-rich repeat	561..585	CDD:275381	7/23 (30%)
		leucine-rich repeat	586..610	CDD:275381	6/23 (26%)
		leucine-rich repeat	636..661	CDD:275381	1/4 (25%)
Amn1	NP_001008334.2	leucine-rich repeat	10..35	CDD:275381	5/20 (25%)
		leucine-rich repeat	36..58	CDD:275381	2/21 (10%)
		AMN1	37..257	CDD:187754	65/243 (27%)
		leucine-rich repeat	63..86	CDD:275381	4/24 (17%)
		leucine-rich repeat	87..116	CDD:275381	10/28 (36%)
		leucine-rich repeat	117..142	CDD:275381	11/24 (46%)
		leucine-rich repeat	143..168	CDD:275381	9/24 (38%)
		leucine-rich repeat	169..195	CDD:275381	2/25 (8%)
		leucine-rich repeat	196..221	CDD:275381	11/34 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900