DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and Fbxl19

DIOPT Version :9

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:XP_036008913.1 Gene:Fbxl19 / 233902 MGIID:3039600 Length:696 Species:Mus musculus


Alignment Length:586 Identity:123/586 - (20%)
Similarity:190/586 - (32%) Gaps:202/586 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 AASPAGATPTPAAPSGKTSVMERVTNALCGGGNSNSNSGSNSSNSNTSSASATAATSPASNANPP 109
            |::...|.|:|:....|....:|:...|....:::|:|..:.|:|::|..|.:...:|....|  
Mouse   292 ASAEGPAVPSPSPQREKLERFKRMCQLLERVPDTSSSSSDSDSDSDSSGTSLSEDEAPGEARN-- 354

  Fly   110 QTPDKPSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQHMQLQQSQQQHLQLQASTLINSN 174
              ..:|:||||   |.....||:..::..|                                   
Mouse   355 --GRRPARGSS---GEKENRGGRRAIRPGT----------------------------------- 379

  Fly   175 HHVMVGPAPPTGMPLGAPPTPTVKSIAKQMNITIPGGGVNPGSPTFSTMGMVAAQKAAASAGGTP 239
                  ..|....|||..|.|....:.:.: :..|     |.||...|:.:.|...         
Mouse   380 ------GGPLLSWPLGPAPPPRPPQLERHV-VRPP-----PRSPEPDTLPLAAGSD--------- 423

  Fly   240 LQLRKQLPNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQLMLDDRFLSRFFQYFSPYERRI 304
                                             ||.|..:          ..|.||:..|.|..:
Mouse   424 ---------------------------------HPLPRAA----------WLRVFQHLGPRELCV 445

  Fly   305 LAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGKLYNSLIRRGFHALGLVGASDEDAL 369
            ..:||..|        ..|        |.:.|..|..|..:      |:......|.|       
Mouse   446 CMRVCRTW--------SRW--------CYDKRLWPRMDLSR------RKSLTPPMLSG------- 481

  Fly   370 DVVHSFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVSL 434
             ||...|.|      |.|..:.:|.:.|..||:.||.|.||.|:||:.::.:.|.:...|.:..|
Mouse   482 -VVRRQPRA------LDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGSAPLPALRLL 539

  Fly   435 SLADCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGI 499
            .|....::.|..:..:  |||.           .|.     .|.|:.|..  |||...||...|:
Mouse   540 DLRWIEDVKDSQLREL--LLPP-----------PDT-----KPGQTESRG--RLQGVAELRLAGL 584

  Fly   500 VNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEE- 563
                               :|||..:.|:..:..:|.|||||.|..:.|.|:..:....:.|.| 
Mouse   585 -------------------ELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRET 630

  Fly   564 ---LTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSS 625
               |.|..|..:||          ....||.| |.::|...|      |:.:.||...|..|.::
Mouse   631 LVHLNLAGCHRLTD----------HCLPLFRR-CPRLRRLDL------RSCRQLSPEACARLAAA 678

  Fly   626 G 626
            |
Mouse   679 G 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 leucine-rich repeat 382..406 CDD:275381 7/23 (30%)
AMN1 383..600 CDD:187754 57/220 (26%)
leucine-rich repeat 431..456 CDD:275381 5/24 (21%)
leucine-rich repeat 457..482 CDD:275381 3/24 (13%)
leucine-rich repeat 483..508 CDD:275381 6/24 (25%)
leucine-rich repeat 509..534 CDD:275381 4/24 (17%)
leucine-rich repeat 535..560 CDD:275381 9/24 (38%)
leucine-rich repeat 561..585 CDD:275381 7/27 (26%)
leucine-rich repeat 586..610 CDD:275381 6/23 (26%)
leucine-rich repeat 636..661 CDD:275381
Fbxl19XP_036008913.1 zf-CXXC <52..79 CDD:366873
PHD_FXL19 89..150 CDD:277115
F-box-like 426..467 CDD:403981 13/66 (20%)
AMN1 468..667 CDD:187754 66/274 (24%)
leucine-rich repeat 488..511 CDD:275381 8/28 (29%)
leucine-rich repeat 512..535 CDD:275381 7/22 (32%)
leucine-rich repeat 573..600 CDD:275381 9/45 (20%)
leucine-rich repeat 601..627 CDD:275381 9/25 (36%)
leucine-rich repeat 631..655 CDD:275381 9/34 (26%)
leucine-rich repeat 656..680 CDD:275381 8/30 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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